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Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 529–576 of 1013 trials
Enrolling by Invitation·N/A·ketamine
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
Medical University of Gdansk
Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Enrolling by Invitation·N/A·ketamine
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Erasmus Medical Center
Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
Vanderbilt University Medical Center
Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·Phase 2·ketamine
Ketamine HCl Prolonged Release Oral Tablets for CRPS
University of Southern California
Complex Regional Pain Syndromes
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
PainHealthy Volunteers
Not Yet Recruiting·Phase 4·ketamine
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
New York State Psychiatric Institute
Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 3·ketamine
Morphine or Ketamine for Analgesia
Columbia University
Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Not Yet Recruiting·Phase 4·ketamine
Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities
University of Sao Paulo
Suicide PreventionKetamineCrisis Response Plan
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine
KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study
Helsinki University Central Hospital
Drug Drug Interaction
Not Yet Recruiting·Phase 4·ketamine
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
University of Missouri-Columbia
Spine Surgery
Not Yet Recruiting·Early Phase 1·ketamine
The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.
National and Kapodistrian University of Athens
Opioid-Refractory Chronic Cancer-Related Pain
Not Yet Recruiting·Phase 2·ketamine
Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.
Fondation Lenval
TraumatologyWounds and InjuryFractures Bone+4 more
Not Yet Recruiting·N/A·ketamine
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Nanjing First Hospital, Nanjing Medical University
Post Induction Hypotension
Not Yet Recruiting·Phase 4·ketamine
Ketamine in Central Sensitization
University Hospitals Cleveland Medical Center
EndometriosisChronic Pelvic Pain
Not Yet Recruiting·Early Phase 1·ketamine
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
University of Pennsylvania
Major Depressive Disorder (MDD)
Not Yet Recruiting·N/A·ketamine
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
Sohag University
Postoperative Sore Throat
Not Yet Recruiting·Phase 2·ketamine
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Opioid Use Disorder
Not Yet Recruiting·Phase 3·ketamine
Optimal Timing of Ketamine Initiation for SCD Pain
Boston Children's Hospital
Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 3·ketamine
Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy
Assiut University
Pain
Not Yet Recruiting·Phase 3·ketamine
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
Zagazig University
Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine
Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine
Prospective Study of Induction Medications Used in the Trauma RSI
University of Southern California
TraumaRapid Sequence Intubation
Not Yet Recruiting·Phase 1·ketamine
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
Liaquat National Hospital & Medical College
SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·Phase 1·ketamine
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Kansas City Heart Rhythm Research Foundation
Pain Management
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·ketamine
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
Assiut University
Orofacial Pain
Not Yet Recruiting·Phase 3·ketamine
Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain
Tehran University of Medical Sciences
PainDigital Block
Not Yet Recruiting·Phase 1·ketamine
Ketamine Biomarker Validation
Soterix Medical
Treatment Resistant Depression (TRD)
Not Yet Recruiting·Phase 4·ketamine
Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）
Chinese PLA General Hospital
Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
Ain Shams University
Upper Gastrointestinal EndoscopyAnesthesia
Not Yet Recruiting·Phase 4·ketamine
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
Assiut University
Varicocelectomy
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·N/A·ketamine
Ketodex Versus Opioid Based Anesthesia in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.
Cairo University
Morbid Obesity
Not Yet Recruiting·Phase 4·ketamine
Ketamine for the Treatment of Refractory Status Epilepticus
Thomas Jefferson University
Refractory Status Epilepticus
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·ketamine
Ketamine Sedation in the ICU (KANINE) RCT
McMaster University
Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 3·ketamine
Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Depressive Disorder
Not Yet Recruiting·Phase 4·ketamine
The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression
The First Hospital of Jilin University
DepressedBariatric Surgery
Not Yet Recruiting·N/A·ketamine
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
IVO JURISIC
Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Anqing Municipal Hospital
EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 4·ketamine
Ketamine for Postherpetic Neuralgia With Depression
Huazhong University of Science and Technology
Depression DisordersHerpetic Neuralgia
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.