Not Yet RecruitingN/Aketamine

Prospective Study of Induction Medications Used in the Trauma RSI

NCT ID

NCT04291521

Target Enrollment

7,000 participants

Start Date

2026-01-01

Est. Completion

2028-07-30

About This Study

To compare the outcomes of the use of propofol, etomidate, and ketamine as induction agents for adult trauma patients undergoing intubation within 24 hours of admission. The primary goal is to determine the ideal agent that should be used in this patient population for intubations.

Conditions Studied

TraumaRapid Sequence Intubation

Interventions

•Ketamine
•Etomidate
•Propofol

Eligibility

Age:18 Years - N/A

Healthy Volunteers:Yes

View full eligibility criteria

Inclusion Criteria:

* Trauma patients \>=18 yo requiring intubation within 24 hours of admission in either the ED or OR
* Patients received propofol, etomidate, or ketamine for induction agent

Exclusion Criteria:

* Patients who were intubated without induction agent medications
* Patients intubated outside of the hospital or in the field
* Patients who were intubated with an induction agent other than etomidate, ketamine, or propofol

Study Locations (1)

Keck School of Medicine of the University of Southern California

Los Angeles, California, United States