Not Yet RecruitingPhase 1ketamine

Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.

Sponsored by Liaquat National Hospital & Medical College

NCT ID
NCT07180095
Target Enrollment
60 participants
Start Date
2026-01-01
Est. Completion
2026-07-30

About This Study

This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population. Hypothesis is Intranal dexmedetomidine is better than intranasal ketamine in producing preoperative sedation in pediatric patients undergoing surgery under general anesthesia.

Conditions Studied

SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic EffectSedation and Analgesia

Interventions

  • •Intranasal dexmedetomidine
  • •Intranasal ketamine

Eligibility

Age:2 Years - 6 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria:

* American society of Anesthesiologist (ASA) class-I and II
* Children 2-6 years of age undergoing elective surgery

Exclusion Criteria:

* Known hypersensitivity to study drugs
* Refusal of consent
* Known renal, hepatic or cardiac dysfunction
* Nasal deformity or pathology
* Recent upper respiratory infection (within 2 weeks)
* Children undergoing neurosurgery or ophthalmic surgery

Interested in this trial?

Contact the study team to learn more about eligibility and enrollment.

View on ClinicalTrials.gov
Data Source
ClinicalTrials.gov

Last updated from source

Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery. | Huxley