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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 913960 of 1695 trials
Not Yet Recruiting·Phase 2·ketamine

Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.

Fondation Lenval

TraumatologyWounds and InjuryFractures Bone+4 more
Not Yet Recruiting·N/A·Other

Ketodex Versus Ketofol in Adolescent Gastrointestinal Endoscopy

Giresun University

Procedural SedationGastrointestinal Endoscopy
Not Yet Recruiting·Phase 4·ketamine

Ketamine in Central Sensitization

University Hospitals Cleveland Medical Center

EndometriosisChronic Pelvic Pain
Not Yet Recruiting·N/A·ketamine

Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery

Nanjing First Hospital, Nanjing Medical University

Post Induction Hypotension
Not Yet Recruiting·N/A·ketamine

Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat

Sohag University

Postoperative Sore Throat
Not Yet Recruiting·Early Phase 1·ketamine

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

University of Pennsylvania

Major Depressive Disorder (MDD)
Not Yet Recruiting·N/A·Other

Influence of Therapeutic Failure on the Psychosocial Experience in Multiple Sclerosis

University Hospital, Caen

Multiple Sclerosis
Not Yet Recruiting·Phase 3·ketamine

Optimal Timing of Ketamine Initiation for SCD Pain

Boston Children's Hospital

Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 2·ketamine

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

University of California, San Diego

Opioid Use Disorder
Not Yet Recruiting·Phase 3·ketamine

Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy

Assiut University

Pain
Not Yet Recruiting·Phase 3·ketamine

Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia

Zagazig University

Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine

Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine

Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Phase 2·psilocybin

Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter

NYU Langone Health

Stuttering
Not Yet Recruiting·N/A·ketamine

Prospective Study of Induction Medications Used in the Trauma RSI

University of Southern California

TraumaRapid Sequence Intubation
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin to Treat Depression in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Not Yet Recruiting·Phase 1·ketamine

Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.

Liaquat National Hospital & Medical College

SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·Phase 1·Other

Magnesium Sulfate in Pediatric Burn Dressing Changes

Hennepin Healthcare Research Institute

Pediatric Burns
Not Yet Recruiting·N/A·Other

Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries With Cardiopulmonary Bypass in Enhanced Recovery After Surgeries

Ain Shams University

CABGDexmedetomidineKetamine+2 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study

Oregon Health and Science University

Chronic Pelvic Pain
Not Yet Recruiting·Phase 2·psilocybin

Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy

Kyle Greenway

Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·Phase 2·ketamine

Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain

Assiut University

Orofacial Pain
Not Yet Recruiting·Phase 1·ketamine

Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain

Kansas City Heart Rhythm Research Foundation

Pain Management
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 2·ketamine

Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression

University of Rochester

Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin for Treatment of OCD-2

Francisco A Moreno

Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 3·ketamine

Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain

Tehran University of Medical Sciences

PainDigital Block
Not Yet Recruiting·Phase 1·ketamine

Ketamine Biomarker Validation

Soterix Medical

Treatment Resistant Depression (TRD)
Not Yet Recruiting·N/A·Other

Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2

University Hospital, Clermont-Ferrand

Ischemic StrokeAnterior Cerebral CirculationGeneral Anesthesia+2 more
Not Yet Recruiting·Phase 4·ketamine

Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT(ESSENCE)

Chinese PLA General Hospital

Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine

Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures

Ain Shams University

Upper Gastrointestinal EndoscopyAnesthesia
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Not Yet Recruiting·Phase 2·ketamine

Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder

University Hospital, Toulouse

Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·Phase 4·ketamine

Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial

Assiut University

Varicocelectomy
Not Yet Recruiting·Phase 2·Other

Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002

Global Coalition for Adaptive Research

Post Traumatic Stress Disorder
Not Yet Recruiting·N/A·ketamine

Ketodex Versus Opioid Based Anesthesia in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Cairo University

Morbid Obesity
Not Yet Recruiting·N/A·Other

Intravenous Sedation and Analgesia Versus Local Anesthesia During Microwave Ablation of Benign Thyroid Nodules

Suez University

Benign Thyroid Nodule
Not Yet Recruiting·Phase 4·ketamine

Ketamine for the Treatment of Refractory Status Epilepticus

Thomas Jefferson University

Refractory Status Epilepticus
Not Yet Recruiting·N/A·Other

Complex Regional Pain Syndrome: Analgesic Outcome

Ciusss de L'Est de l'Île de Montréal

Chronic PainComplex Regional Pain Syndrome
Not Yet Recruiting·Phase 2·psilocybin

Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)

Centre Hospitalier St Anne

Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin as a Treatment for Chronic Pain in Smokers

Yale University

Smokers With Chronic Pain
Not Yet Recruiting·N/A·LSD

Microdosing LSD in Women With Premenstrual Disorders

Friederike Holze

PMSPMDD
Not Yet Recruiting·Phase 3·psilocybin

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Lakshmi N Yatham

Bipolar II Depression
Not Yet Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD

Queen's University

Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·ketamine

Ketamine Sedation in the ICU (KANINE) RCT

McMaster University

Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 3·ketamine

Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Depressive Disorder
Not Yet Recruiting·Phase 4·ketamine

The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression

The First Hospital of Jilin University

DepressedBariatric Surgery
Not Yet Recruiting·Phase 3·Other

A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis

University Hospital, Montpellier

Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.