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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 337384 of 1013 trials
Completed·Phase 1·ketamine

Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study

University of Calgary

PainTraumatic Limb Injury
Completed·Phase 1·ketamine

A Pharmacokinetic, Safety and Tolerability Study of Esketamine in Healthy Elderly and Adult Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 3·ketamine

The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial

Washington University School of Medicine

Delirium
Completed·Phase 2·ketamine

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

Janssen Research & Development, LLC

Treatment Resistant Depressive Disorder
Completed·N/A·ketamine

The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures

Massachusetts General Hospital

Mechanical VentilationAirway PatencyRespiratory Depression
Completed·Phase 2·ketamine

Ketamine as a Rapidly-Acting Antidepressant in Depressed Emergency Department Patients

NYU Langone Health

Depression
Completed·Phase 2·ketamine

Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)

New York State Psychiatric Institute

Obsessive-Compulsive Disorder
Completed·Phase 2·ketamine

Novel Topical Therapies for the Treatment of Genital Pain

University of Rochester

Female Genital Diseases
Completed·Phase 1·ketamine

A Study to Assess the Pharmacokinetics of Intranasally Administered Esketamine in Healthy Japanese and Caucasian Volunteers

Janssen Research & Development, LLC

Healthy Volunteers
Completed·Phase 4·ketamine

Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study

Northwestern University

PainObesityHypoxia
Completed·N/A·ketamine

CYP2B6 Polymorphisms in Ketamine

Washington University School of Medicine

Healthy Volunteers
Completed·Phase 1·ketamine

A Study to Evaluate the Pharmacokinetics of Intranasal Esketamine Administered With and Without a Nasal Guide on the Intranasal Device

Janssen Research & Development, LLC

Healthy
Completed·N/A·ketamine

Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study

Albert Einstein Healthcare Network

Emergence ReactionProcedural Sedation
Completed·N/A·ketamine

Pharmacokinetic Alterations During ECMO

Columbia University

Acute Respiratory Failure
Completed·Phase 4·ketamine

Comparing Ketamine and Propofol Anesthesia for Electroconvulsive Therapy

University of Saskatchewan

Treatment Resistant Depression
Completed·Phase 4·ketamine

Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department

Carilion Clinic

Acute PainPain
Completed·N/A·ketamine

Anesthetics in Rhytidoplasty - A Comparison Study

Mercy Facial Plastic Surgery Center

Rhytidoplasty
Completed·Phase 4·ketamine

Ketamine Versus Etomidate for Rapid Sequence Intubation

Hennepin Healthcare Research Institute

Airway ControlAnesthesiaIntubation+1 more
Completed·N/A·ketamine

Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor

The University of Texas Health Science Center at San Antonio

Acute CholecystitisChronic Cholecystitis
Completed·Phase 1·ketamine

Ketamine for Suicidality in Bipolar Depression

New York State Psychiatric Institute

Bipolar DisorderMajor Depressive EpisodeSuicidal Ideation
Completed·Phase 4·ketamine

Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.

Balikesir University

Arthroscopy
Completed·N/A·ketamine

The Effects of the Anesthetic Ketamine in Young Children Undergoing Procedural Sedation

The Hospital for Sick Children

Trauma
Completed·Phase 1·ketamine

Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults

Takeda

Ketamine-Induced Brain Activity ChangesPsychotic-like Symptoms
Completed·Phase 4·ketamine

Management of Pain in Lumbar Arthrodesis

Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta

Pain, Postoperative
Completed·Early Phase 1·ketamine

Examining The Effect Of Ketamine On Glutamate/Glutamine Cycling

Yale University

Depression
Completed·Phase 4·ketamine

Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial

University Hospital, Basel, Switzerland

Postoperative Delirium
Completed·Phase 4·ketamine

Ketamine and Propofol for Upper Endoscopy

The Hospital for Sick Children

Anesthesia
Completed·Phase 2·ketamine

Ketamine Plus Lithium in Treatment-Resistant Depression

Icahn School of Medicine at Mount Sinai

Depression
Completed·Phase 2·ketamine

Action of Ketamine in Treatment-Resistant Depression

University of Ottawa

Treatment-resistant Depression
Completed·Phase 4·ketamine

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

Albany Medical College

Idiopathic ScoliosisPost-operative Pain
Completed·Early Phase 1·ketamine

Characterizing Clinical and Pharmacological Neuroimaging Biomarkers

Yale University

Cognitive Impairment
Completed·Phase 4·ketamine

Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department

Antonios Likourezos

Pain
Completed·Phase 4·ketamine

ACL Repair and Multimodal Analgesia

University of Wisconsin, Madison

Pain
Completed·Phase 4·ketamine

NMDA Antagonists in Bipolar Depression

New York State Psychiatric Institute

Bipolar Disorder
Completed·N/A·ketamine

The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Aga Khan University

Cholelithiasis
Completed·N/A·ketamine

Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation

Inje University

Psychomotor Agitation
Completed·N/A·ketamine

Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Completed·Phase 2·ketamine

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine

Isfahan University of Medical Sciences

Closed Multiple Fractures of Upper and Lower Limbs
Completed·Phase 1·ketamine

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 1·ketamine

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

Biogen

Schizophrenia
Completed·Phase 4·ketamine

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

HealthPartners Institute

Pain
Completed·Phase 2·ketamine

A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion

NYU Langone Health

Spinal Fusion
Completed·Phase 4·ketamine

Intra-nasal Ketamine for Analgesia in the Emergency Department

Lions Gate Hospital

Pain
Completed·Phase 1·ketamine

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

Rhode Island Hospital

Pain
Completed·Phase 2·ketamine

A Study of Ketamine in Patients With Treatment-resistant Depression

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·Phase 1·ketamine

Changes in Striatal [11C]ORM-13070 Binding Elicited by Changing Levels of Endogenous Noradrenaline

University of Turku

Changes in Striatal [11C]ORM-13070 Binding.
Completed·N/A·ketamine

Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris

University of Washington

Monitoring, Intraoperative
Completed·Phase 2·ketamine

Low Dose Ketamine VR Analgesia During Burn Care Procedure

National Institute of General Medical Sciences (NIGMS)

Burn
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.