CompletedPhase 2ketamine

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine

Sponsored by Isfahan University of Medical Sciences

NCT ID
NCT01807429
Target Enrollment
236 participants
Start Date
2012-12
Est. Completion
2013-02

About This Study

the investigators assessed the effects of low-dose IV ketamine-midazolam versus morphine on pain control in trauma patients with closed limb fracture(s); and also compared the incidence of adverse events (mainly cardio pulmonary ) between two groups.

Conditions Studied

Closed Multiple Fractures of Upper and Lower Limbs

Interventions

  • •Ketamine-midazolam
  • •Morphine

Eligibility

Age:18 Years - 60 Years
Healthy Volunteers:Yes
View full eligibility criteria
Inclusion Criteria:

1. Between 18 and 60 years
2. Patients with closed limb fracture(s)
3. VAS score of at least 6

Exclusion Criteria:

1. Acute pulmonary infection
2. Previous coronary artery diseases,ACS,congestive heart failure,
3. suspected aortic dissection
4. History of uncontrolled hypertention or blood pressure \> 140/90mmHg
5. Brain injury with focal neurological deficit or loss of consciousness
6. Central nervous system mass lesion,hydrocephalus, or other states with increased intracranial pressure
7. Glaucoma and acute globe injury
8. History of porphyria
9. Previous hyperthyroidism or thyroid hormone replacement
10. Pregnancy or laction
11. Major psychiatric disorder
12. Previous allergic reaction to the agents administered in the study
13. Patient declined to provide written informed conse

This trial is not recruiting

This study has completed enrollment. Check back for results or find similar trials.

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Data Source
ClinicalTrials.gov

Last updated from source

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine | Huxley