CompletedPhase 1ketamine

Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study

Sponsored by University of Calgary

NCT ID
NCT02033434
Target Enrollment
30 participants
Start Date
2014-03-01
Est. Completion
2017-09-01

About This Study

The investigators hypothesize that intra-nasal ketamine, for analgesia of patients with moderate to severe pain in an alpine setting, will provide a clinically significant reduction in pain and provide an effective and feasible alternative to intravenous opioids. The investigators wish to know: 1. Is our study protocol feasible to study INK in a mountain, prehospital care environment? 2. What estimate can be made of recruitment rates? 3. Does studying the use of INK interfere with or delay care at Whistler/Blackcomb? 4. Is intra-nasal ketamine an effective and safe method for controlling pain in our study population and setting? 5. Does intranasal ketamine provide a clinically significant reduction in pain or do patients require additional IV narcotics for extraction? 6. Are there any significant changes in vital signs after administration of intra-nasal ketamine 7. Does the use of intra-nasal ketamine reduce time of patient extraction and transport in the alpine pre-hospital setting? 8. Are there any long term sequelae of INK at one week?

Conditions Studied

PainTraumatic Limb Injury

Interventions

  • Intranasal Ketamine

Eligibility

Age:18 Years - 79 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria:

* traumatic extremity injury
* age greater than 18 years old
* moderate or severe pain (VNRS 5 or greater)

Exclusion Criteria:

* need for an intravenous catheter as judged by treating physician
* pregnancy
* unable to speak English
* shoulder dislocations,
* previous hypersensitivity, intolerance, or allergy to ketamine,
* structural or functional nasal occlusion,
* inability to understand the VNRS,
* Glasgow Coma Scale \<15,
* inability to give informed consent
* history of schizophrenia

Study Locations (1)

Whistler Blackcomb
Whistler, British Columbia, Canada

This trial is not recruiting

This study has completed enrollment. Check back for results or find similar trials.

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Data Source
ClinicalTrials.gov

Last updated from source