Ketamine Versus Etomidate for Rapid Sequence Intubation

Inclusion Criteria:

* 18 years of age
* Undergoing rapid sequence intubation (RSI) in the Emergency Department

Exclusion Criteria:

* Known contraindication to ketamine or etomidate
* Patient has a condition in which an increase in heart rate or blood pressure would be hazardous, as judged by the treating physician
* Patient is known or suspected of having increased intracranial pressure, based on the history and physical examination performed by the treating physician.
* Females of child-bearing age, defined as 18-50 years, who do not have a documented pregnancy test in this institution confirming that they are not pregnant or who do not have a confirmed surgical procedure preventing pregnancy, i.e., tubal ligation, hysterectomy. The timing of the pregnancy test at which the investigative team will consider a subject to be non-pregnant is a documented negative test during current hospitalization or upon direct transfer from outside institution during current illness.
* Patient declines participation in the trial by wearing a bracelet marked "KvE declined"
* Prisoner