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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 289336 of 1013 trials
Completed·Phase 2·ketamine

Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD)

Icahn School of Medicine at Mount Sinai

Posttraumatic Stress Disorder (PTSD)
Completed·Phase 1·ketamine

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Minneapolis Veterans Affairs Medical Center

Depressive Disorder, Treatment-ResistantStress Disorders, Post-Traumatic
Completed·Phase 2·ketamine

miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome

University of Alabama at Birmingham

Major Depressive Disorder
Completed·N/A·ketamine

Ketamine: Comparison of IV Push vs. IV Drip

Antonios Likourezos

Pain
Completed·Phase 2·ketamine

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

VA Office of Research and Development

Treatment-resistant Depression
Completed·Early Phase 1·ketamine

Ketamine for Depression Relapse Prevention Following ECT

St Patrick's Hospital, Ireland

Depression
Completed·Phase 2·ketamine

Intranasal Ketamine as a Sedative for Venipuncture

Hospital de Clinicas de Porto Alegre

Respiratory Tract DiseaseAcute PainDiseases of the Digestive System
Completed·Phase 3·ketamine

Effects of Ketamine in the Acute Phase of Suicidal Ideation

Centre Hospitalier Universitaire de Nīmes

Suicidal Ideation
Completed·Phase 1·ketamine

Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)

New York State Psychiatric Institute

Obsessive-Compulsive Disorder
Completed·N/A·ketamine

Ketamine and fMRI for Neuropathic Pain

University Health Network, Toronto

Neuralgia
Completed·Phase 2·ketamine

Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder

Pouya Movahed Rad

Depressive Disorder, Major
Completed·Phase 1·ketamine

Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Intravenous Ketamine

Yale University

Depression
Completed·Early Phase 1·ketamine

Ketamine Infusion for Social Anxiety Disorder

Yale University

Social Anxiety Disorder
Completed·Phase 1·ketamine

Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

VA Office of Research and Development

Major Depressive DisorderAlcohol Use Disorder
Completed·Early Phase 1·ketamine

A Multimodal Neuroimaging Study of Brain Activation Patterns Under Ketamine

Psychiatric University Hospital, Zurich

Major Depressive Disorder
Completed·Phase 4·ketamine

A Comparison of the Sedation During Endoscopy in Children

Kanuni Sultan Suleyman Training and Research Hospital

Failed Moderate Sedation During Procedure
Completed·Phase 1·ketamine

A Study to Evaluate the Absolute Bioavailability of Intranasal and Oral Esketamine and the Effects of Clarithromycin on the Pharmacokinetics of Intranasal Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

VA Pittsburgh Healthcare System

Acute PainChronic PainHernia+2 more
Completed·Phase 4·ketamine

Ketamine For Acute Treatment of Pain in Emergency Department

The Brooklyn Hospital Center

Pain
Completed·Phase 4·ketamine

Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy

University of Manitoba

Obstructive Sleep Apnea Syndrome
Completed·Phase 2·ketamine

Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)

Massachusetts General Hospital

Treatment Resistant Depression
Completed·Phase 1·ketamine

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 2·ketamine

Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction

iX Biopharma Ltd.

Pain
Completed·N/A·ketamine

Evaluating Ketamine and Psychological Sequelae

Defense and Veterans Center for Integrative Pain Management

Pain, Ketamine Infusion, Psychologic Sequelae
Completed·Phase 2·ketamine

Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy

NYU Langone Health

PainPostoperative Depression
Completed·N/A·ketamine

Cognitive Biases Under Ketamine

Centre Hospitalier St Anne

Healthy Subjects
Completed·N/A·ketamine

Ketamine's Actions on Rumination Mechanisms as an Antidepressant

King's College London

Remission in Depression
Completed·Phase 2·ketamine

Ketamine for Depression and Suicide Risk

Mayo Clinic

DepressionSuicide
Completed·Phase 2·ketamine

Ketamine in Adolescents With Treatment-Resistant Depression

University of Minnesota

Major Depressive Disorder
Completed·Phase 1·ketamine

Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·N/A·ketamine

Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers

National Taiwan University

Substance Use Disorders
Completed·Phase 4·ketamine

A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion

NYU Langone Health

Postoperative Pain
Completed·N/A·ketamine

Effects of Propofol and Ketofol on Core Body Temperature in MRI

Istanbul University

Children
Completed·Phase 1·ketamine

Single Dose Administration of Ketamine 10, 20, 40 and 80 mg and 5 mg Solution for Infusion in 15 Healthy Subjects

University Medicine Greifswald

Healthy
Completed·N/A·ketamine

Retrospective Evaluation of Ketamine Effectiveness for the Treatment of Acute Battlefield Related Pain

Defense and Veterans Center for Integrative Pain Management

Pain, AcuteAnalgesiaAmputation, Traumatic+2 more
Completed·Phase 3·ketamine

Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department

University of British Columbia

Emergency Department Procedural SedationFracture Reduction
Completed·Phase 2·ketamine

A Study to Assess the Analgesic Properties of a Sublingual Wafer Formulation of Ketamine Following Third Molar Extraction

Lotus Clinical Research, LLC

Pain
Completed·N/A·ketamine

Pre-Emptive Analgesia in Ano-Rectal Surgery

University of Vermont

HemorrhoidsFissure in AnoRectal Fistula+1 more
Completed·Phase 1·ketamine

Study to Assess the Effects of Allergic Rhinitis and Co-administration of Mometasone or Oxymetazoline on the Pharmacokinetics, Safety, and Tolerability of Intranasal Esketamine

Janssen Research & Development, LLC

Allergic Rhinitis
Completed·Phase 1·ketamine

Biomarkers of Fast Acting Therapies in Major Depression

University of California, Los Angeles

Major Depressive Disorder
Completed·Phase 1·ketamine

A Study to Evaluate the Effect of Intranasal Esketamine on Cognitive Functioning in Healthy Subjects

Janssen Research & Development, LLC

Healthy
Completed·Phase 2·ketamine

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·Phase 4·ketamine

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Rigshospitalet, Denmark

Postoperative PainChronic PainAnalgesics
Completed·Phase 4·ketamine

Biomarker Assessment of Glutamatergic Target Engagement

New York State Psychiatric Institute

Healthy Controls
Completed·N/A·ketamine

Plasma Concentration of Ketamine and Norketamine .

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Chronic Pain
Completed·Phase 4·ketamine

Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric

Universitas Diponegoro

Specified SedativeHypnotic
Completed·Phase 2·ketamine

Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial

Mayo Clinic

Critical Illness
Completed·N/A·ketamine

Effects of Ketamine on Eye Movements, Perception and Brain Function

University of Bonn

Functional Neuroimaging
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.