CompletedN/Aketamine

Ketamine: Comparison of IV Push vs. IV Drip

NCT ID

NCT02363270

Target Enrollment

48 participants

Start Date

2015-04-01

Est. Completion

2017-02-28

About This Study

Our previous published research comparing the efficacy of intravenous ketamine to morphine has shown ketamine to provide equivalent relief of moderate to severe acute pain in emergency medicine patients. Secondary analysis of the previous published research has also revealed ketamine to have statistically more side effects. The investigators believe that increasing the time of administration of the ketamine, from a push injection to a drip infusion, will minimize the side effects experienced by recipients of ketamine.

Conditions Studied

Pain

Interventions

•Ketamine

Eligibility

Age:18 Years - 65 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Emergency Medicine patients
* Adult patients (18-65 years of age)
* Moderate to severe pain (Numeric Pain Rating Score =5).
* Patients must be awake, alert and oriented to time, place and person.
* Patients must be able to demonstrate understanding of the informed consent, and also able to verbalize how much pain they are having on the 10 point Numeric Rating Pain Scale, and the nature of the side effects they may be experiencing from the IV analgesia

Exclusion Criteria:

* Patients with cognitive deficits that are not able to demonstrate understanding as described above.
* Patient's reported weight of less than 45kg or more than 115kg.
* Patients with altered mental status, alcohol intoxication, eye trauma.
* Patients with hemodynamic instability (Systolic Blood pressure \<90), and malignant hypertension.
* allergy to ketamine
* Pregnancy or breast feeding.

Study Locations (1)

Maimonides Medical Center

Brooklyn, New York, United States