CompletedN/Aketamine

Evaluating Ketamine and Psychological Sequelae

NCT ID

NCT04053400

Target Enrollment

159 participants

Start Date

2014-12

Est. Completion

2017-09-13

About This Study

The purpose of this study is to examine the relationship between the use of intravenous infusion of sub-anesthetic dosages of ketamine given for pain to combat casualties and emerging symptoms of Post-Traumatic Stress Disorder (PTSD), depression, anxiety, sleep disruption, and risk of alcohol abuse as identified with behavioral health screening tools. Although ketamine has gained popularity as an analgesic agent, literature related to its psychological impact is sparse.

Conditions Studied

Pain, Ketamine Infusion, Psychologic Sequelae

Interventions

•Ketamine

Eligibility

Age:18 Years - N/A

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

Group I. Ketamine Group

* Active duty military service member injured in theater and treated at WRAMC or at WRNMMC
* 18 years of age or older
* Completed the PBBHA or PDHAT initial and follow up assessment post aerovac from theater
* Received ketamine infusion to treat pain after aero-evacuation for inpatient medical care between Sep 2005 and June 2014
* Received ketamine before completion of the PDHAT or PDBHA follow-up assessment
* ISS scores are available for each individual

Group II. Non-Ketamine Comparison Group

* Active duty military service member injured in theater and treated at WRAMC or at WRNMMC
* 18 years of age or older
* Completed the PBBHA or PDHAT initial and follow up assessment post aerovac from theater
* Did not receive ketamine treatment for pain after aero-evacuation for inpatient medical care before follow-up
* ISS are available for each individual
* Patient will have ISS scores similar to a Ketamine Group patient and a similar timing of injury to the same Ketamine Group patient.

Exclusion Criteria:

* Not treated by WRNMMC/WRAMC hospital staff between Sep 2005 and June 2014
* Not active duty, activated National Guard, or activated Reserve service members
* Younger than 18 years of age
* Did not complete the PDBHA or PDHAT initial and follow-up assessments
* ISS scores are not available

Study Locations (1)

Walter Reed National Military Medical Center

Bethesda, Maryland, United States