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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 817864 of 1695 trials
Completed·N/A·ketamine

Ketamine Pharmacokinetics in Children Having Heart Surgery

Arkansas Children's Hospital Research Institute

C.Surgical Procedure; Cardiac
Completed·N/A·MDMA

Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging

University of Zurich

Amphetamine-Related DisordersAmphetamine Abuse
Completed·Phase 2·ketamine

Polyamine-free Diet to Prevent Post Surgery Hyperalgesia

University Hospital, Bordeaux

Breast CancerSurgery
Completed·Phase 1·ketamine

N-acetylcysteine and NMDA Antagonist Interactions

Yale University

Cognitive Dysfunction
Completed·N/A·ketamine

Analgesic Efficacy of Intravenous Lidocaine and/or Ketamine

University of Lausanne Hospitals

Postoperative Pain
Completed·Phase 4·ketamine

Anesthetics and Auditory, Visceral, and Heat Evoked Potentials

Technical University of Munich

Healthy
Completed·Phase 4·ketamine

Ketamine on Acute Pain in Females and Males

Ullevaal University Hospital

Mouth and Tooth DiseasesTooth, Impacted
Completed·N/A·ketamine

Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation

Queen's University

FracturesDislocationsAbscess+2 more
Completed·Phase 1·ketamine

Rapid Antidepressant Effects of Ketamine in Major Depression

National Institute of Mental Health (NIMH)

DepressionMood DisordersMajor Depresssion
Completed·Phase 2·ketamine

Use of Ketamine Prior to Cardiopulmonary Bypass in Children

Arkansas Children's Hospital Research Institute

Ventricular Septal Defect
Completed·Phase 3·ketamine

Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy

University Hospital, Clermont-Ferrand

Partial Pneumonectomy Under Lateral or Posterolateral Thoracotomy.
Completed·Phase 1·psilocybin

Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Anxiety
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 4·ketamine

Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls

University of Aarhus

Odontalgia
Completed·Phase 1·MDMA

Neurobiology and Pharmacokinets of Acute MDMA Administration

National Institute on Drug Abuse (NIDA)

Substance-Related Disorders
Completed·Phase 3·ketamine

Administration of Ketamine to Prevent the Post-operative Pain

Institut Bergonié

Postoperative PainBreast Cancer
Completed·N/A·ketamine

Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine

Assistance Publique - Hôpitaux de Paris

Postoperative Pain
Completed·Phase 1·MDMA

-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms

Parc de Salut Mar

MetabolismInteraction
Completed·Phase 4·ketamine

Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

Vilnius University

Opiate Dependence
Completed·Phase 4·ketamine

Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids

Washington University School of Medicine

Psychoses, Substance-Induced
Completed·N/A·Other

Examining the Risk of Skin Cancer in Multiple Sclerosis Patients Using Fingolimod: a Population-Based Study

University of British Columbia

Multiple SclerosisSkin CancerSkin Cancer Melanoma+3 more
Completed·Phase 3·ketamine

KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain

Assistance Publique - Hôpitaux de Paris

KetamineChronic Post Thoracotomy PainThoracotomy+2 more
Completed·Phase 1·ketamine

Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects

Yale University

Healthy Subjects
Completed·N/A·ketamine

Ondansetron Reduce Vomiting Associated With Ketamine PSA

University of Colorado, Denver

Conscious Sedation
Completed·N/A·MDMA

The NeXT Study; The Netherlands XTC Toxicity Study

UMC Utrecht

Ecstasy (Drug)N-Methyl-3,4-MethylenedioxymethamphetaminePsychopathology
Completed·Phase 4·ketamine

Preoperative Ketamine Has no Preemptive Analgesic Effect in Patients Undergoing Colon Surgery.

Hospital Arquitecto Marcide

Pain, Postoperative
Completed·Phase 1·MDMA

Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·N/A·ketamine

Ketamine/Placebo Family History Positive Study

Yale University

Alcoholism
Completed·Phase 2·ketamine

Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain

Javelin Pharmaceuticals

Pain, Postoperative
Enrolling by Invitation·N/A·ketamine

Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation

University of California, San Diego

Suicidal Ideation
Enrolling by Invitation·N/A·psilocybin

Salivary Oxytocin as a Biomarker of Psychedelic Treatment

University of Geneva, Switzerland

Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 1·psilocybin

PRoMiSS: Psilocybin and the Role of Music in Set and Setting

Johns Hopkins University

PsilocybinMusic Intervention
Enrolling by Invitation·Phase 3·psilocybin

Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

Cybin IRL Limited

Major Depressive Disorder
Enrolling by Invitation·Phase 2·ketamine

Ketamine Effects on Learning In Eating Disorders

Amanda Downey, MD

Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·Phase 1·psilocybin

Psilocybin With Intracranial Neural Sensing

Joshua Woolley, MD, PhD

Chronic Pain
Enrolling by Invitation·Phase 1·Other

Induction of Dreaming With EEG and Anesthesia in Healthy Adults

Stanford University

Healthy Volunteers
Enrolling by Invitation·Phase 2·MDMA

High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD

ARQ National Psychotrauma Centre

Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·Phase 2·ketamine

Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19

University of Texas at Austin

Long COVID
Enrolling by Invitation·N/A·ketamine

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

Psyrin Inc.

Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·N/A·ketamine

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics

University of Pittsburgh

Depression
Enrolling by Invitation·N/A·ketamine

Using Virtual Reality to Control the Audio-visual Inputs During Ketamine/Esketamine Treatment

Yale University

Depression
Enrolling by Invitation·Phase 2·MDMA

MDMA Plus Exposure Therapy for PTSD

Emory University

PTSD
Enrolling by Invitation·N/A·ketamine

Long Term Follow Up KET-PD

Yale University

Parkinson's DiseaseDepression
Enrolling by Invitation·Phase 4·ketamine

Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

Brigham and Women's Hospital

Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine

Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

Kernel

DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·Other

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

University of Kansas Medical Center

AnesthesiaTubal Ligation
Enrolling by Invitation·N/A·psilocybin

The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training

Felix Mueller

Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·ketamine

Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)

Medical University of Gdansk

Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.