CompletedPhase 4ketamine

Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

NCT ID

NCT00300794

Target Enrollment

60 participants

Start Date

2003-02

Est. Completion

2006-06

About This Study

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Conditions Studied

Opiate Dependence

Interventions

•Ketamine

Eligibility

Age:18 Years - 35 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Diagnosed opiate dependence according to ICD 10 and/or DSM 4;
* Duration of substance abuse more than 1 year
* No or minor co-morbidities;
* Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion Criteria:

* Current history of long acting opiate or poly-substance abuse;
* Acute medical or surgical condition;
* Pregnancy;
* Breastfeeding.

Study Locations (1)

Vilnius University Emergency Hospital

Vilnius, Lithuania