Administration of Ketamine to Prevent the Post-operative Pain

About This Study

The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse effects. The purpose is to evaluate the analgesic effect of a receptor NMDA's antagonist ( ketamine)

Conditions Studied

Interventions

• •Ketamine
• •Saline solution

Eligibility

Inclusion criteria:

* Patients 18 years older
* ASA class 1 or 2
* with surgery of breast cancer (mastectomy or tumorectomy)

Exclusion criteria:

.Kétamine hypersensitivity

* Major psychiatric disorders
* Major cardio-vascular disorders
* Major neurologic disorders
* Major ocular disorders
* Morphine in pre-operative period

Study Locations (1)