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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 721768 of 1695 trials
Completed·N/A·ketamine

Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine.

Dr. Horst Schmidt Klinik GmbH

Acute PainChronic PainNeuropathic Pain
Completed·N/A·ketamine

Neuromodulation to Facilitate the Effect of Ketamine

The Neuroscience Center, LLC

DepressionChronic PainSubstance Abuse
Completed·Phase 2·ketamine

The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam

University Hospital, Basel, Switzerland

Analgesia, Patient-controlledSpinal Stenosis
Completed·Phase 3·ketamine

Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department

University of Colorado, Denver

Procedural Sedation and Analgesia
Completed·Phase 2·ketamine

The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy

University Hospital, Lille

Pain, Postoperative
Completed·N/A·MDMA

Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·Phase 2·MDMA

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·N/A·MDMA

Naturalistic Study Into the Hangover Effects of MDMA

Utrecht Institute for Pharmaceutical Sciences

Hangover
Completed·Phase 3·ketamine

Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia

Lions Gate Hospital

Emergency Department Procedural SedationFracture ReductionAbscess Incision and Drainage+1 more
Completed·N/A·ketamine

A Comparison of Ketofol (Ketamine and Propofol Admixture) Versus Propofol as Induction Agents on Hemodynamic Parameters

Mayo Clinic

Blood Pressure
Completed·Phase 2·MDMA

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 4·ketamine

Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation

Hennepin Healthcare Research Institute

Procedural Sedation
Completed·Phase 4·ketamine

Anesthesia for Retinopathy of Prematurity

TC Erciyes University

Retinopathy
Completed·Phase 4·DMT

A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis

Novartis Pharmaceuticals

Relapsing Forms of Multiple Sclerosis
Completed·Phase 4·ketamine

Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children

Children's Hospital of Michigan

Moderate, Deep Sedation
Completed·Phase 4·ketamine

Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation

Université de Montréal

Pain
Completed·Phase 1·MDMA

Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·N/A·MDMA

Effects of MDMA on Social and Emotional Processing

University of Chicago

Drug Addiction
Completed·Phase 1·LSD

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Shire

Mucopolysaccharidosis (MPS)
Completed·Phase 4·ketamine

Alternative Sedation During Bronchoscopy

University of Pennsylvania

Sedation
Completed·Phase 4·ketamine

Effects of Ketamine and Risperidone on Cognition

University of Manchester

Healthy VolunteersSchizophrenia
Completed·N/A·ketamine

Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation

Craig J. Huang

Sialorrhea
Completed·Phase 2·ketamine

Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer

Dartmouth-Hitchcock Medical Center

MucositisHead and Neck Cancer
Completed·N/A·ketamine

Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial

University of Utah

Sedation
Completed·Phase 4·ketamine

Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depression

Northwell Health

Unipolar DepressionBipolar Depression
Completed·Phase 2·ketamine

Nasal Administration of Sufentanil+Ketamine for Procedure-related Pain in Children

Danish University of Pharmaceutical Sciences

Pain
Completed·N/A·MDMA

Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.

California Pacific Medical Center Research Institute

MDMA Discontinuation Syndrome
Completed·Phase 1·ketamine

Ketamine for Low Mood States in the ER

Yale University

DepressionSuicide Ideation
Completed·Phase 2·ketamine

Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)

New York State Psychiatric Institute

Obsessive-Compulsive Disorder
Completed·Early Phase 1·ketamine

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

AstraZeneca

HealthyMemory Impairment
Completed·Phase 1·ketamine

Ketamine Challenge Study With JNJ-40411813

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Perceptual DisordersConfusionSchizophrenia
Completed·Phase 2·Other

Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Multiple Myeloma
Completed·Phase 4·ketamine

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia

Julia Finkel

Idiopathic ScoliosisSpondylolisthesis
Completed·N/A·ketamine

Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Post Operative PainHyperalgesia
Completed·Phase 1·ketamine

Immunomodulatory Properties of Ketamine in Sepsis

Beth Israel Deaconess Medical Center

Sepsis
Completed·Phase 1·ketamine

Study Where Pharmaco Magnetic Resonance Imaging (MRI) Effects of AZD6765 Will be Compared to Placebo in Depressive Male and Female Subjects

AstraZeneca

Depression
Completed·Phase 1·MDMA

Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·Phase 1·ketamine

The Effect of Ketamine on Attentiveness

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Schizophrenia
Completed·Phase 2·Other

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

New York State Psychiatric Institute

Obsessive-Compulsive Disorder
Completed·Phase 1·psilocybin

Psilocybin and Spiritual Practice

Johns Hopkins University

Healthy
Completed·Phase 4·ketamine

Perioperative Electroacupuncture on Postoperative Analgesia in Prostatectomy

G.Gennimatas General Hospital

Pain, Postoperative
Completed·Phase 1·MDMA

Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-related DisordersAmphetamine-related Disorders
Completed·Phase 1·LSD

A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVA

BioMarin Pharmaceutical

MPS IV A
Completed·Phase 2·ketamine

Oral Ketamine Administration in Patients With Peripheral Neuropathic Pain

University Hospital, Toulouse

Neuropathic Pain
Completed·Early Phase 1·psilocybin

Psilocybin Cancer Anxiety Study

NYU Langone Health

Cancer
Completed·Phase 2·ketamine

Ketamine Infusion for Obsessive-Compulsive Disorder

Yale University

Obsessive-compulsive Disorder
Completed·Phase 3·ketamine

The Preemptive Analgetic Potency of Low Dose S-Ketamine

Medical University of Graz

Pain
Completed·N/A·MDMA

Role of Serotonin in Acute and Subacute MDMA Effects

California Pacific Medical Center Research Institute

MDMA Mechanism of Action
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.