CompletedPhase 4ketamine
Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children
Sponsored by Children's Hospital of Michigan
NCT ID
NCT02519595
Target Enrollment
182 participants
Start Date
2010-08
Est. Completion
2012-08
About This Study
There is a wide variation of published IV ketamine dosing regimens used for procedural sedation in children in the Emergency Department (ED). The purpose of the study was to compare the efficacy, duration of sedation and adverse events between the three commonly administered doses of IV ketamine (1 mg/kg, 1.5 mg/kg and 2 mg/kg) using the traditional administration method of 30-60 second infusion for ED sedation in children.
Conditions Studied
Interventions
- •Ketamine IV 1mg/kg
- •Ketamine IV 1.5mg/kg
- •Ketamine IV 2mg/kg
Eligibility
Age:3 Years - 18 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * Children 3 -18 years of age * Belonging to American Society of Anesthesiologists (ASA) classification 1 or 2 * Receiving IV ketamine for procedural sedation for orthopedic procedures, * Incision and Drainage of skin abscess and laceration repair Exclusion Criteria: * Contraindications to use of Ketamine * Parents or legal guardian not available or declined to provide informed consent * Child declined to provide assent, * Patients that received intramuscular ketamine, * Patient that received benzodiazepines in addition to ketamine * Children weighing \>100 kilogram * Children with developmental disabilities.