CompletedEarly Phase 1ketamine

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

NCT ID

NCT00985933

Target Enrollment

20 participants

Start Date

2010-02

Est. Completion

2011-04

About This Study

The purpose of this study is to assess if ketamine will induce, in healthy volunteers, impairment of working memory and if the drug AZD8529 will block the effects of ketamine on working memory as assessed by functional magnetic resonance imaging (fMRI).

Conditions Studied

HealthyMemory Impairment

Interventions

•AZD8529
•Placebo to match AZD8529

Eligibility

Age:21 Years - 45 Years

Healthy Volunteers:Yes

View full eligibility criteria

Inclusion Criteria:

* Right handed
* 12th grade education or equivalent
* Able to read and write English as primary language

Exclusion Criteria:

* History of head injury
* Substance abuse or dependence
* History of claustrophobia

Study Locations (1)

Research Site

New Haven, Connecticut, United States