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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 289336 of 1695 trials
Completed·N/A·DMT

Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)

Delphinus Medical Technologies, Inc.

Breast Cancer DetectionDense Breast ParenchymaBenign Breast Findings+2 more
Completed·Phase 4·ketamine

Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy

Medical University of Warsaw

ObesityPostoperative PainPostoperative Nausea+2 more
Completed·N/A·ketamine

Ketamine Infusion as Sedative Analgesic in Severe ARDS

Interfaith Medical Center

Intensive Care Unit SyndromeMechanical Ventilation ComplicationSedatives and Hypnotics Causing Adverse Effects in Therapeutic Use+1 more
Completed·Phase 3·ketamine

Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery

Christine Oryhan

Opioid Use, UnspecifiedBariatric Surgery CandidateAnesthesia
Completed·Early Phase 1·ketamine

The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women

The Ketamine Research Foundation

KetamineLactation
Completed·N/A·ketamine

Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control

CHRISTUS Health

Abdominal Pain
Completed·N/A·ketamine

A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders

Medical University of Gdansk

Treatment Resistant DepressionBipolar DepressionKetamine+1 more
Completed·N/A·ketamine

Chart Review of Patients Undergoing Ketamine Infusions

Brain and Cognition Discovery Foundation

Major Depressive DisorderBipolar DisorderObsessive-Compulsive Disorder+1 more
Completed·Phase 1·ketamine

Effect of Ketamine Intranasal Spray in Treatment of Chronic Cluster Headache

CCH Pharmaceuticals

Cluster Headache
Completed·Phase 3·Other

Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use

Prisma Health-Upstate

Opioid Use
Completed·Phase 1·DMT

Clinical Study of GH001 in Depression

GH Research Ireland Limited

Treatment Resistant DepressionMajor Depressive DisorderDepression
Completed·N/A·Other

Validation of a Shared Decision-Making Tool for Multiple Sclerosis

Shared Decision Making Resources

Multiple Sclerosis
Completed·Phase 2·LSD

LSD Therapy for Persons Suffering From Major Depression

University Hospital, Basel, Switzerland

Major Depressive Disorder
Completed·Phase 4·Other

IPACK Study in Total Knee Arthroplasty Patients

University Health Network, Toronto

Knee Replacement Arthroplasty
Completed·Early Phase 1·MDMA

Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 4·ketamine

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

MercyOne Des Moines Medical Center

DepressionDepression SevereDepression Acute+2 more
Completed·Phase 2·psilocybin

A Study of Psilocybin for Major Depressive Disorder (MDD)

Usona Institute

Depressive Disorder, Major
Completed·Phase 2·ketamine

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

Grace Lim, MD, MS

Obstetric PainPostpartum DepressionBreastfeeding+5 more
Completed·Early Phase 1·ketamine

EEG Characteristics in ECT

University of New Mexico

Electroconvulsive TherapyDirect Current ElectroencephalogramKetamine+1 more
Completed·Phase 1·ketamine

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

University of Minnesota

Post-Traumatic Stress DisordersMajor Depressive Disorder
Completed·Phase 1·ketamine

THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis

Yale University

CannabisKetamine
Completed·Phase 2·ketamine

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Clexio Biosciences Ltd.

Adjunctive Treatment of Major Depressive Disorder
Completed·Phase 3·ketamine

Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy

University of Patras

Lung DiseasesDiagnosisAnesthesia
Completed·Phase 2·ketamine

Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus

New York State Psychiatric Institute

Tinnitus
Completed·Phase 1·psilocybin

Effects of Psilocybin in Anorexia Nervosa

Johns Hopkins University

Anorexia Nervosa
Completed·Phase 4·ketamine

Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

Stanford University

Major Depressive DisorderSurgeryOrthopedic Disorder
Completed·Early Phase 1·ketamine

The PATHFINDER Study: A Feasibility Trial

Beth Israel Deaconess Medical Center

Coronary Artery DiseaseDelirium
Completed·N/A·ketamine

Stanford Regulating Circuits of the Brain Study- Ketamine

Stanford University

Healthy
Completed·Early Phase 1·MDMA

Effects of Drugs on Responses to Brain and Emotional Processes

University of Chicago

Autism Spectrum DisorderHealthy
Completed·Phase 2·ketamine

Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects

Icahn School of Medicine at Mount Sinai

Healthy Volunteers
Completed·Phase 2·ketamine

A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients

Arlyne Thung

Adenoid Hypertrophy
Completed·Phase 4·ketamine

Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy

Brooke Army Medical Center

Conscious SedationPatient SatisfactionKetamine
Completed·Phase 1·LSD

Stem Cell Gene Therapy for Cystinosis

University of California, San Diego

Lysosomal Storage DiseasesCystinosis
Completed·Phase 1·psilocybin

Effects of SERT Inhibition on the Subjective Response to Psilocybin in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·ketamine

Biomarkers of Response to Ketamine in Depression: MRI and Blood Assays Before and After Open Label Intranasal Ketamine

Dan Iosifescu

Depressive Disorder, Treatment-Resistant
Completed·Phase 4·ketamine

Effects of Ketamine on Mentalizing and Metacognition in Healthy Volunteers

University Hospital, Bonn

Ketamine-Induced Psychotic DisorderSocial CognitionTheory of Mind
Completed·N/A·Other

Comparison of Two Sedation Versus Placebo Techniques During Cataract Surgery Under Local Anesthesia

University of Liege

SedationCataract
Completed·Phase 1·ketamine

The Effects of Sedatives on Tobacco Use Disorder

Wake Forest University Health Sciences

Tobacco Use Disorder
Completed·N/A·ketamine

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

Medical College of Wisconsin

Behavior, ChildAnxiety
Completed·Phase 4·ketamine

Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

Antonios Likourezos

Pain
Completed·N/A·ketamine

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

Klarisana Physician Services PLLC

Stress Disorders, Post-TraumaticAnxiety Disorders
Completed·Phase 1·Other

Mood Effects of Serotonin Agonists Extended

University of Chicago

Healthy
Completed·Phase 4·ketamine

Nebulized Sub-dissociative Dose Ketamine for Treating Pain

Antonios Likourezos

Pain
Completed·N/A·DMT

Prospective Stratification of Infectious Risks in Multiple Sclerosis

University Hospital, Basel, Switzerland

Multiple Sclerosis
Completed·Phase 1·ketamine

Ketamine and Prolonged Exposure in PTSD

Minneapolis Veterans Affairs Medical Center

Post-traumatic Stress Disorder
Completed·N/A·ketamine

Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)

Azienda Ospedaliera di Padova

AnalgesiaKetamine ToxicityBronchospasm+1 more
Completed·Phase 2·ketamine

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Celon Pharma SA

Bipolar Depression
Completed·N/A·ketamine

Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Postpartum Hemorrhage
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.