CompletedPhase 4ketamine

Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery

NCT ID

NCT03861988

Target Enrollment

45 participants

Start Date

2019-08-22

Est. Completion

2022-09-27

About This Study

This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery. Half of participants will receive a ketamine infusion during surgery, while the other half will receive a placebo (normal saline) during surgery.

Conditions Studied

Major Depressive DisorderSurgeryOrthopedic Disorder

Interventions

•Ketamine
•Normal saline (placebo)

Eligibility

Age:18 Years - 80 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Patient presenting for non-cardiac, non-intracranial surgery
* Major Depressive Disorder

Exclusion Criteria:

* Pregnant of breastfeeding women

Study Locations (1)

Stanford University

Stanford, California, United States