CompletedPhase 2ketamine

A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients

NCT ID

NCT03714919

Target Enrollment

10 participants

Start Date

2019-08-02

Est. Completion

2019-11-10

About This Study

This proposed study will assess analgesic efficacy of a multi-modal, non-opioid analgesic regimen for providing surgical analgesia in pediatric patients undergoing adenoidectomy and to assess recovery characteristics in the post-anesthesia care unit (PACU) and at home following surgery.

Conditions Studied

Adenoid Hypertrophy

Interventions

•Dextromethorphan
•Acetaminophen
•Dexmedetomidine
•Ketamine

Eligibility

Age:4 Years - 8 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

1. Patients undergoing adenoidectomy ± bilateral ear tube placement
2. Have a parent/guardian who are compliant with routine medical care, capable of subjective evaluation and able to read, understand and sign the informed consent in accordance with IRB regulations

Exclusion Criteria:

1. An American Society of Anesthesiologists Physical Status ≥ 4 (severe disease that is life threatening);
2. A known hypersensitivity or allergy to any of the study medications;
3. A history of chronic opioid use prior to surgery;
4. Coexisting renal or hepatic disease;
5. Morbid obesity (BMI% ≥ 99).

Study Locations (1)

Nationwide Children's Hospital

Columbus, Ohio, United States