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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145192 of 1013 trials
Completed·Phase 4·ketamine

Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

Antonios Likourezos

Pain
Completed·N/A·ketamine

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

Klarisana Physician Services PLLC

Stress Disorders, Post-TraumaticAnxiety Disorders
Completed·Phase 4·ketamine

Nebulized Sub-dissociative Dose Ketamine for Treating Pain

Antonios Likourezos

Pain
Completed·Phase 1·ketamine

Ketamine and Prolonged Exposure in PTSD

Minneapolis Veterans Affairs Medical Center

Post-traumatic Stress Disorder
Completed·N/A·ketamine

Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)

Azienda Ospedaliera di Padova

AnalgesiaKetamine ToxicityBronchospasm+1 more
Completed·Phase 2·ketamine

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Celon Pharma SA

Bipolar Depression
Completed·N/A·ketamine

Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Postpartum Hemorrhage
Completed·Early Phase 1·ketamine

Ketamine for Refractory Chronic Migraine: a Pilot Study

Thomas Jefferson University

Migraine Headache With Intractable Migraine
Completed·Phase 2·ketamine

A Study to Evaluate Ketamine for the Treatment of Rett Syndrome

Rett Syndrome Research Trust

Rett Syndrome
Completed·Phase 2·ketamine

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression

Celon Pharma SA

Major Depressive Disorder
Completed·Phase 1·ketamine

A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS)

Neurocrine Biosciences

Healthy Volunteers
Completed·Phase 2·ketamine

Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression

Novartis Pharmaceuticals

Depressive Disorder, Treatment-Resistant
Completed·N/A·ketamine

The Anti-inflammatory Effect of Anesthetics in Abdominal Surgery

University Hospital Dubrava

Colorectal Cancer
Completed·Phase 3·ketamine

Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine

The Cleveland Clinic

Reducing Psychological Side Effects of Ketamine
Completed·Phase 1·ketamine

A Study to Assess Electrophysiology, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of SAGE-718 Using Ketamine Challenge in Healthy Subjects

Supernus Pharmaceuticals, Inc.

Healthy Volunteer
Completed·Phase 1·ketamine

A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 1·ketamine

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial

Yale University

Depressive Disorder, MajorPost Traumatic Stress DisorderBipolar Disorder
Completed·Phase 1·ketamine

A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Supernus Pharmaceuticals, Inc.

Healthy Volunteer
Completed·Phase 1·ketamine

Assessment of Effect of Rapastinel on Driving Performance

Naurex, Inc, an affiliate of Allergan plc

Driving Performance
Completed·Phase 1·ketamine

Assessment of Abuse Potential of Rapastinel in Humans

Naurex, Inc, an affiliate of Allergan plc

Human Abuse Potential
Completed·Phase 2·ketamine

EEG Studies of Ketamine General Anesthesia

Massachusetts General Hospital

Anesthesia
Completed·Phase 4·ketamine

Sub-dissociative Dose Ketamine Dosing Study

Loyola University

Acute Pain
Completed·Phase 4·ketamine

Impact of the Use of Ketamine in Laparoscopic Surgery.

Universidade do Porto

Quality of Recovery
Completed·Phase 4·ketamine

Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption

Ciusss de L'Est de l'Île de Montréal

Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption
Completed·Phase 1·ketamine

A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Supernus Pharmaceuticals, Inc.

Healthy Volunteer
Completed·N/A·ketamine

Assessment of Ketamine and Propofol Sedation During LISA Method (Less Invasive Surfactant Administration)

University Hospital, Montpellier

Premature Neonate
Completed·N/A·ketamine

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

Psych Atlanta

Treatment Resistant Depression
Completed·Phase 1·ketamine

Ketamine for Treatment of MS Fatigue

Johns Hopkins University

Multiple SclerosisFatigue
Completed·Phase 2·ketamine

Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children

Athens General Children's Hospital "Pan. & Aglaia Kyriakou"

Effect of Anesthesia in Postoperative PainEffect of Anesthesia in Extubation TimeEffect of Anesthesia in Discharge Time From Postanesthesia Care Unit+2 more
Completed·Phase 2·ketamine

Study of Ketamine for Depression in Cancer Patients Receiving Palliative Care

University Health Network, Toronto

DepressionCancerPalliative Care
Completed·Phase 4·ketamine

Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery

University of Arkansas

Anterior Cervical Discectomy and Fusion (ACDF)
Completed·Phase 3·ketamine

Intranasal Ketamine and Fracture Reduction in Pediatric Emergencies (KETAPED)

Fondation Lenval

Fractures, Closed
Completed·Phase 4·ketamine

Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries

Northwestern University

PainPostpartum Depression
Completed·Phase 4·ketamine

Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Ketamine

University of Texas Southwestern Medical Center

HemorrhageHealthy
Completed·Phase 2·ketamine

Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?

Helse Møre og Romsdal HF

Rotator Cuff TendinitisChronic Pain
Completed·Phase 2·ketamine

Rapid Agitation Control With Ketamine in the Emergency Department

David Barbic

Violent Aggressive BehaviorKetamine
Completed·Phase 3·ketamine

A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Completed·Phase 2·ketamine

EEG Studies of Sevoflurane-Induced General Anesthesia

Massachusetts General Hospital

Anesthesia
Completed·Phase 3·ketamine

Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse

The University of Texas Health Science Center, Houston

Suicidal IdeationDepressionAlcohol Abuse
Completed·Phase 2·ketamine

Perioperative Ketamine for Pain With Gastric Bypass

Mayo Clinic

Laparoscopic Gastric Bypass SurgeryKetamine
Completed·Phase 1·ketamine

The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia

NeuroWave Systems Inc.

Anesthesia
Completed·Phase 2·ketamine

Ketamine for Endoscopic Sedation in Outpatient Adult Endoscopy.

Brooke Army Medical Center

Administration and Dosage of KetamineEndoscopic Sedation
Completed·Phase 3·ketamine

Sedation MRI - Propofol Versus Propofol-Ketamin in Children

Achim Schmitz

Sedation
Completed·N/A·ketamine

Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio

University Hospital, Ghent

Procedural Sedation and Analgesia
Completed·Phase 2·ketamine

Sequential Therapy for the Treatment of Severe Bipolar Depression.

NeuroRx, Inc.

Bipolar DepressionSuicidal IdeasSuicidal Ideation+1 more
Completed·Phase 3·ketamine

Ketamine Infusion for Comorbid PTSD and Chronic Pain

VA Ann Arbor Healthcare System

PTSDChronic Pain
Completed·N/A·ketamine

Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery

Universidad Pública de Navarra

Postoperative PainThoracic SurgeryMultimodal Analgesia+1 more
Completed·Phase 4·ketamine

Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation

South East Area Health Education Center, Wilmington, NC

Intubation Complication
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.