CompletedPhase 4ketamine
Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Ketamine
Sponsored by University of Texas Southwestern Medical Center
NCT ID
NCT03621085
Target Enrollment
43 participants
Start Date
2018-06-01
Est. Completion
2021-06-30
About This Study
The purpose of this project is to test how ketamine, an analgesics currently employed in the pre-hospital setting by the US Army, alters the capacity to tolerate a hemorrhagic insult in humans.
Conditions Studied
Interventions
- •Ketamine Hydrochloride
- •Placebo
Eligibility
Age:18 Years - 45 Years
Healthy Volunteers:Yes
View full eligibility criteria
Inclusion Criteria: * 18-45 years of age * Healthy * Non-obese (body mass index less than 30 kg/m2) * Body mass greater than or equal to 65 kg Exclusion Criteria: * Subjects not in the defined age range * Subjects who have cardiac, respiratory, neurological and/or metabolic illnesses * Any known history of renal or hepatic insufficiency/disease * Pregnancy or breast feeding * Body mass less than 65 kg * Current smokers, as well as individuals who regularly smoked within the past 3 years * Positive urine drug screen * Currently taking pain modifying medication(s)
Study Locations (1)
Texas Health Presbyterian Hospital Dallas
Dallas, Texas, United States