CompletedPhase 4ketamine

Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption

NCT ID

NCT03781635

Target Enrollment

50 participants

Start Date

2018-09-25

Est. Completion

2019-09-30

About This Study

The aim of the present study is to show that i.v. ketamine boluses might lead to significant and clinically relevant BIS index increase that might lead to an increase in anesthesia dosing (halogenous gas) when compared to an i.v. continuous infusion of ketamine without any bolus.

Conditions Studied

Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption

Interventions

•bolus of intravenous ketamine
•continuous infusion of intravenous ketamine

Eligibility

Age:18 Years - N/A

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* ASA I to III
* Patients above 18yo
* Gender female or male
* Abdominal general, urological or gynecological surgery with epidural placement

Exclusion Criteria:

* BMI \<18 or \>35
* Chronic neurological or psychiatric disorder or history of stroke
* Use of psychotropic drugs within 2 weeks prior surgery
* Allergy to ketamine or its excipients or any drug of the anesthesia protocol of this study
* Any contra-indication or patient's refusal for epidural placement

Study Locations (1)

Hopital Maisonneuve Rosemont, CIUSSS de l'Est de l'Ile de Montreal

Montreal East, Quebec, Canada