CompletedPhase 3ketamine

Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine

NCT ID

NCT03831854

Target Enrollment

46 participants

Start Date

2019-01-24

Est. Completion

2020-12-31

About This Study

Patient will receive lamotrigine vs. placebo with small sips of water. Lamotrigine reaches peak level 1-4 hours after oral administration.

Conditions Studied

Reducing Psychological Side Effects of Ketamine

Interventions

•Lamotrigine 300 MG
•Placebo
•Ketamine

Eligibility

Age:18 Years - 65 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* 18 -65 Years of age
* Planned overnight hospital stay

Exclusion Criteria:

* Pregnant and planning to become pregnant
* No known History of seizure
* No known History of Schizophrenia
* No known History of unstable angina
* Patients taking Antiepileptic medications
* Known history of Lamotrigine intake in past.
* Any history of allergic reaction to lamotrigine in the past.

Study Locations (1)

Cleveland Clinic

Cleveland, Ohio, United States