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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 9611008 of 1013 trials
Withdrawn·Phase 2·ketamine

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study

Zylorion Health

Treatment Resistant Major Depressive Disorder
Withdrawn·Early Phase 1·ketamine

Scheduled Intranasal Ketamine

Sanford Health

PainTrauma
Withdrawn·Phase 1·ketamine

A Study in Healthy Men to Test Whether BI 474121 Can Reverse the Memory Problems Caused by Ketamine

Boehringer Ingelheim

Healthy
Withdrawn·Phase 2·ketamine

Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial

Northwell Health

Cancer of Head and NeckMucositis OralPharyngeal Mucositis
Withdrawn·Phase 4·ketamine

Preoperative Ketamine and Perioperative Depression

Northwestern University

Depressive Disorder
Withdrawn·Phase 1·ketamine

A Study to Assess Feasibility of Using Clinician-directed and Digital Application Supported Cognitive Behavior Therapy (CBT) in Conjunction With Esketamine in Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depression
Withdrawn·Phase 2·ketamine

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

Wake Forest University Health Sciences

Radical Prostatectomies
Withdrawn·Phase 2·ketamine

Intramuscular Ketamine for Suicidal Ideation

Icahn School of Medicine at Mount Sinai

Suicidal Ideation
Withdrawn·Phase 4·ketamine

Bubiket Study: Ultrasound Guided Fascia Iliaca Nerve Block With Bupivacaine and Adjuvant Ketamine vs. Bupivacaine Alone

Antonios Likourezos

Pain, Musculoskeletal
Withdrawn·Phase 2·ketamine

Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures

The University of Texas Health Science Center, Houston

Pain, Acute
Withdrawn·Phase 4·ketamine

Ketamine Infusion for Sickle Cell Pain Crisis

Duke University

Anemia; Sickle-Cell, With CrisisAcute Pain
Withdrawn·Phase 3·ketamine

ECT vs. Esketamine

Medical University Innsbruck

Treatment Resistant DepressionMajor Depressive Disorder
Withdrawn·Phase 2·ketamine

Compare the Efficacy and Safety of Intranasal Esketamine in Chronic Opioid Refractory Pain

University Hospital, Basel, Switzerland

Cancer Pain
Withdrawn·N/A·ketamine

Low Dose Ketamine Infusion for the Treatment of Resistant Depression

Loma Linda University

Depression
Withdrawn·Phase 1·ketamine

Intravenous Ketamine Effects on Functional Neuroanatomy

Neurological Associates of West Los Angeles

Depression
Withdrawn·Early Phase 1·ketamine

Intranasal Ketamine for Suicidal Ideation in Veterans

Bronx Veterans Medical Research Foundation, Inc

Suicidal Ideation
Withdrawn·Phase 3·ketamine

The Role of Ketamine as an Adjuvant Therapy for Children With Acute Status Asthmaticus

Augusta University

Status Asthmaticus
Withdrawn·Phase 3·ketamine

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Janssen-Cilag International NV

Depressive Disorder, Treatment-Resistant
Withdrawn·Phase 2·ketamine

Single-dose Ketamine for the Reduction of Pain and Depression in the Emergency Department

Maria Pacella

Acute PainDepression
Withdrawn·Phase 3·ketamine

Endogenous Opioid Modulation by Ketamine

University of Utah

Major Depressive Disorder
Withdrawn·Phase 4·ketamine

Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine

Santa Barbara Cottage Hospital

Alcohol Withdrawal Syndrome
Withdrawn·Phase 2·ketamine

ED Treatment of Suicidal Patients With Ketamine Infusion

University of California, Davis

SuicideSuicidal Ideation
Withdrawn·Phase 4·ketamine

Pre-hospital Nebulized Ketamine for Pain

Antonios Likourezos

Pain
Withdrawn·Phase 3·ketamine

Ketamine Sickle Cell Disease

University of South Florida

SC DiseasePain, Chronic
Withdrawn·Phase 4·ketamine

Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia

Tampere University Hospital

Pain, Postoperative
Withdrawn·Phase 4·ketamine

Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal

University of Colorado, Denver

Alcohol Withdrawal
Withdrawn·Phase 2·ketamine

Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine

William V. Bobo, M.D.

Treatment Resistant Depression
Withdrawn·Phase 2·ketamine

Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus

University of Alabama at Birmingham

Refractory Epilepsy
Withdrawn·Phase 4·ketamine

Exploring the Safety and Efficacy of Low-dose Ketamine Infusions for Pain Control in Acute Burn Injury

University of Kansas Medical Center

Pain
Withdrawn·Phase 3·ketamine

The Impact of Ketamine on the Reward Circuitry of Suicidal Patients

Massachusetts General Hospital

Suicidal IdeationSuicide
Withdrawn·Early Phase 1·ketamine

IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures

Phoenix Children's Hospital

Conscious SedationDistal Radius Fracture
Withdrawn·Early Phase 1·ketamine

Ketamine for Preventing Depression in Patients Undergoing Treatment for Pancreatic or Head and Neck Cancers

Cedars-Sinai Medical Center

Head and Neck CancerPancreatic CancerDepression
Withdrawn·Phase 3·ketamine

A Study to Decrease Suicidal Thinking Using Ketamine

United States Naval Medical Center, San Diego

DepressionSuicide
Withdrawn·N/A·ketamine

Evaluation of Ketamine and Multi-modal Analgesics

University of Florida

Pain
Withdrawn·Phase 4·ketamine

Ketamine in Colorectal Surgery

Medical College of Wisconsin

Acute PainPain, PostoperativeColorectal Surgery
Withdrawn·N/A·ketamine

Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Withdrawn·Phase 4·ketamine

Intranasal Ketamine for Late-Life Depression and Suicidal Ideation

Massachusetts General Hospital

DepressionSuicideSuicidal Ideation
Withdrawn·Phase 3·ketamine

Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain

University of Texas Southwestern Medical Center

Phantom Pain
Withdrawn·Phase 4·ketamine

Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion

Northwestern University

AnesthesiaPainSurgery
Withdrawn·Phase 2·ketamine

Compare the Effect of Propofol vs. "Ketofol" on Hemodynamic Stability During Induction of General Anesthesia

Yale University

Patients With "ASA 3" Designation
Withdrawn·Phase 4·ketamine

A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients

University of Colorado, Denver

Thermal HyperalgesiaAnxietyPain
Withdrawn·Phase 2·ketamine

To Test the Potential Efficacy of Repeated Intranasal Administration of Ketamine as a Treatment for PTSD

Adriana Feder

PTSD
Withdrawn·N/A·ketamine

S Ketamine Use in Total Abdominal Hysterectomy

KK Women's and Children's Hospital

Total Abdominal Hysterectomy
Withdrawn·Phase 4·ketamine

Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital

Hennepin Healthcare Research Institute

Agitation
Withdrawn·Phase 3·ketamine

Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus

Mid-Atlantic Epilepsy and Sleep Center, LLC

EpilepsyStatus Epilepticus
Withdrawn·Phase 3·ketamine

Effectiveness of Ketamine in Malignant Neuropathic Pain Relief

Haukeland University Hospital

Pain, Intractable
Withdrawn·Phase 2·ketamine

Trial of Ketamine and Lithium Therapy in Bipolar Depression

Yale University

Bipolar Depression
Withdrawn·N/A·ketamine

Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients

University of Utah

TraumaPain
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.