WithdrawnPhase 2ketamine
Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus
Sponsored by University of Alabama at Birmingham
NCT ID
NCT03115489
Start Date
2017-05-04
Est. Completion
2021-05-18
About This Study
The study will investigate the efficacy of the N-methyl-D-aspartate receptor antagonist ketamine as a first line agent in refractory status epilepticus versus traditional general anesthetic agents used for burst suppression that target the gamma-aminobutyric acid adrenergic receptors.
Conditions Studied
Interventions
- •Traditional Treatment (Group T)
- •Ketamine Infusion (Group K)
Eligibility
Age:18 Years - 100 Years
Healthy Volunteers:Yes
View full eligibility criteria
Inclusion Criteria: * Patients more than 18 years of age with a diagnosis of status epilepticus * Considered for burst suppression therapy after failing 2 or 3 anti-epileptic medications Exclusion Criteria: * Post anoxic status epilepticus * Pregnant women, as confirmed by urine, or blood human chorionic gonadotropin, ultrasound or physical exam * Prisoners * Age less than 18 years * Allergy or sensitivity to the drug in question
Study Locations (1)
UAB Department of Anesthesiology and Perioperative Medicine
Birmingham, Alabama, United States