WithdrawnPhase 4ketamine

Exploring the Safety and Efficacy of Low-dose Ketamine Infusions for Pain Control in Acute Burn Injury

NCT ID

NCT03095222

Start Date

2017-04-01

Est. Completion

2018-05-24

About This Study

The purpose of this study is to identify the optimal dosing strategy for low-dose ketamine infusions in adult acute burn injury patients when used with usual pain medications.

Conditions Studied

Pain

Interventions

•Ketamine
•Opioids

Eligibility

Age:18 Years - N/A

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Acute burn injury comprising 10-30% of total body surface. Burns severity may include second or third degree burns
* Burn injury must have occurred within 72 hours of enrollment and randomization
* Subjects may be opioid-naïve or opioid non-naïve
* Anticipated stay in the burn unit is greater than 4 days, which is typically the minimum length of stay for patients with this level of burn injury

Exclusion Criteria:

* Burn injury older than 72 hours
* Acute burn injury comprising \>30% total body surface
* Patients who are intubated
* Patients who have contraindication to ketamine administration

Study Locations (1)

University of Kansas Medical Center

Kansas City, Kansas, United States