24 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 140 of 40 trials
Active, Not Recruiting·N/A·psilocybin

Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism

Healing Advocacy Fund

Alcohol Use Disorder
Active, Not Recruiting·Phase 2·psilocybin

Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder

Peggy C Nopoulos

Alcohol Use Disorder
Active, Not Recruiting·Phase 2·psilocybin

Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder

Johns Hopkins University

Major Depressive DisorderAlcohol Use Disorder
Active, Not Recruiting·Phase 2·psilocybin

Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder

Keith Heinzerling

Alcohol Use Disorder
Completed·Phase 2·psilocybin

Psilocybin-assisted Therapy for Treatment of Alcohol Use Disorder

Anders Fink-Jensen, MD, DMSci

Alcohol Use Disorder
Completed·Phase 2·psilocybin

Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients

University of Zurich

Alcohol Use Disorder
Completed·Phase 1·ketamine

The Effects of Sedatives on Tobacco Use Disorder

Wake Forest University Health Sciences

Tobacco Use Disorder
Completed·Phase 2·ketamine

Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

VA Connecticut Healthcare System

Major Depressive DisorderAlcohol Use Disorder
Completed·Phase 1·ketamine

Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

VA Office of Research and Development

Major Depressive DisorderAlcohol Use Disorder
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

Brigham and Women's Hospital

Alcohol Use Disorder
Not Yet Recruiting·Phase 4·Other

Examining Analgesic Synergy and Efficacy in Trauma Care

Wake Forest University Health Sciences

Opioid Use Disorder
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Not Yet Recruiting·Early Phase 1·Other

Transition From Acute to Chronic Opioid Use and Chronic Pain

Jacques E. Chelly

Opioid Use Disorder
Not Yet Recruiting·Phase 2·ketamine

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

University of California, San Diego

Opioid Use Disorder
Not Yet Recruiting·Phase 1·ketamine

Ketamine for Combined Depression and Alcohol Use Disorder

University Hospital of North Norway

DepressionAlcohol Use Disorder
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Alcohol Use Disorder

University of Sydney

Alcohol Use DisorderAlcohol DependenceDepression+1 more
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin

Safety Profile of Psilocybin for Cocaine Use Disorder

University of California, Los Angeles

Cocaine Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Wellcome Leap Psilocybin for OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

NYU Langone Health

Alcohol Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

University of Iowa

Alcohol Use DisorderAlcohol DependenceAlcohol Abuse
Recruiting·Phase 1·psilocybin

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Yale University

Opioid Use Disorder
Recruiting·N/A·ketamine

ACT_for Alcohol Use Disorder and Depression

Centre hospitalier de l'Université de Montréal (CHUM)

Depression - Major Depressive DisorderAlcohol Use Disorder
Recruiting·N/A·psilocybin

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Recruiting·Phase 2·MDMA

MDMA for Co-occurring PTSD and OUD After Childbirth

University of New Mexico

Stress Disorders, Post-TraumaticOpioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder

University of Calgary

Alcohol Use DisorderAlcoholism
Recruiting·Phase 2·psilocybin

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Recruiting·Phase 2·MDMA

MDMA for AUD/PTSD Comorbidity

Carolina L Haass-Koffler

Alcohol Use DisorderPost Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

Dr. med. Marcus Herdener

Cocaine Use DisorderCocaine Dependence
Recruiting·Phase 2·psilocybin

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Johns Hopkins University

Tobacco Use Disorder
Recruiting·Phase 1·psilocybin

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

University of Wisconsin, Madison

Opioid Use Disorder
Terminated·Phase 2·ketamine

Ketamine for OUD and Suicidal Ideation in the ED

Brigham and Women's Hospital

Opioid Use DisorderSuicidal Ideation
Terminated·Phase 1·ketamine

Ketamine for OUD and Comorbid Depression (OUDCD)

University of Maryland, Baltimore

Opioid Use DisorderDepressive Disorder
Unknown·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)

Clairvoyant Therapeutics

Alcohol Use Disorder
Unknown·Phase 1·MDMA

Bristol Imperial MDMA in Alcoholism Study

Imperial College London

Alcohol Use Disorder
Withdrawn·Phase 2·psilocybin

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Withdrawn·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use

Johns Hopkins University

Opioid Use Disorder
Withdrawn·Phase 2·ketamine

Ketamine for the Treatment for Alcohol Use Disorder in the ED

Brigham and Women's Hospital

Alcohol Use Disorder

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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.