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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 385432 of 1695 trials
Completed·Phase 3·ketamine

Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse

The University of Texas Health Science Center, Houston

Suicidal IdeationDepressionAlcohol Abuse
Completed·Phase 2·ketamine

Perioperative Ketamine for Pain With Gastric Bypass

Mayo Clinic

Laparoscopic Gastric Bypass SurgeryKetamine
Completed·Phase 2·MDMA

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 1·ketamine

The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia

NeuroWave Systems Inc.

Anesthesia
Completed·Phase 2·ketamine

Ketamine for Endoscopic Sedation in Outpatient Adult Endoscopy.

Brooke Army Medical Center

Administration and Dosage of KetamineEndoscopic Sedation
Completed·N/A·Other

KETODEX for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery

Ochsner Health System

Emergence DeliriumStrabismus
Completed·Phase 3·ketamine

Sedation MRI - Propofol Versus Propofol-Ketamin in Children

Achim Schmitz

Sedation
Completed·N/A·ketamine

Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio

University Hospital, Ghent

Procedural Sedation and Analgesia
Completed·Phase 2·ketamine

Sequential Therapy for the Treatment of Severe Bipolar Depression.

NeuroRx, Inc.

Bipolar DepressionSuicidal IdeasSuicidal Ideation+1 more
Completed·Phase 3·ketamine

Ketamine Infusion for Comorbid PTSD and Chronic Pain

VA Ann Arbor Healthcare System

PTSDChronic Pain
Completed·Phase 1·psilocybin

Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS Survivors

Joshua Woolley

DistressDepressionGrief
Completed·Phase 4·ketamine

Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation

South East Area Health Education Center, Wilmington, NC

Intubation Complication
Completed·N/A·ketamine

Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery

Universidad Pública de Navarra

Postoperative PainThoracic SurgeryMultimodal Analgesia+1 more
Completed·Phase 1·ketamine

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Celon Pharma SA

Healthy Volunteers
Completed·Phase 1·ketamine

Intravenous Ketamine Plus Neurocognitive Training for Depression

Rebecca Price

Depression
Completed·Early Phase 1·LSD

Role of the Serotonin 5-HT2A Receptor in LSD-induced Altered States of Consciousness (LDR-Study)

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·ketamine

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, Baltimore

Acute Kidney InjuryRenal InsufficiencyRenal Failure+1 more
Completed·Phase 2·MDMA

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Lykos Therapeutics

PTSD
Completed·Phase 4·ketamine

Prehospital Analgesia With Intra-Nasal Ketamine

University of British Columbia

PainAcute Pain
Completed·Phase 4·ketamine

Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain

Allevio Pain Management Clinic

Chronic Neuropathic Pain and Fibromyalgia
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Migraine Headache

Yale University

Migraine Headache
Completed·N/A·DMT

Impact of the Arrival on the French Market of New First Line Oral Treatments on the Delay Between MS Onset and First Disease Modifying Treatment (DMTs) Administration

University Hospital, Caen

C10.114.375.500
Completed·Phase 3·ketamine

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

University of Saskatchewan

AnesthesiaGeneral AnesthesiaAnalgesics, Opioid+14 more
Completed·Phase 2·ketamine

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 1·ketamine

A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)

Massachusetts General Hospital

Depression
Completed·Phase 1·ketamine

Ketamine as an Adjunctive Therapy for Major Depression

St Patrick's Hospital, Ireland

Major Depressive EpisodeUnipolar DepressionBipolar Depression
Completed·Phase 4·Other

Milrinone Versus Dobutamine in Critically Ill Patients

Ottawa Heart Institute Research Corporation

Low Cardiac Output SyndromeCardiogenic ShockAcute Coronary Syndrome+1 more
Completed·Phase 4·ketamine

Effect of Ketamine on Analgesia Post-Cardiac Surgery

Jewish General Hospital

Pain, Postoperative
Completed·Phase 2·Other

Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain

iX Biopharma Ltd.

Acute PainBunionAbdominoplasty
Completed·Phase 4·ketamine

UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study

University of Wisconsin, Madison

UnconsciousnessConsciousness
Completed·Phase 2·psilocybin

Effects of Psilocybin in Major Depressive Disorder

Johns Hopkins University

Major Depressive Disorder
Completed·N/A·ketamine

Ketamine Versus Midazolam for Prehospital Agitation

Hennepin Healthcare Research Institute

Agitation
Completed·Phase 1·ketamine

Intranasal (NAS) Ketamine for Cancer Pain

Emory University

CancerPain
Completed·N/A·Other

The Multiple Sclerosis Continuous Quality Improvement (MSCQI) Collaborative

Dartmouth-Hitchcock Medical Center

Multiple Sclerosis
Completed·Early Phase 1·ketamine

Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

Johns Hopkins University

Lumbar Spinal StenosisLumbar Spinal InstabilityLumbar Spine Degeneration
Completed·Phase 1·psilocybin

Persisting Effects of Psilocybin

Johns Hopkins University

Healthy
Completed·N/A·ketamine

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

Avanti Anesthesia

Cataract
Completed·Phase 1·ketamine

Effects of TS-134 on Ketamine-induced BOLD Signals in Healthy Subjects

Taisho Pharmaceutical R&D Inc.

Healthy Volunteers
Completed·Phase 2·LSD

LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders

University Hospital, Basel, Switzerland

PatientsAnxiety Disorders
Completed·Phase 3·ketamine

54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 3·ketamine

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 4·ketamine

The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.

Mayo Clinic

Major DepressionBipolar I DisorderBipolar II Disorder+1 more
Completed·Phase 3·ketamine

Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Chronic Pain
Completed·N/A·Other

Opioid Free Anesthesia and Continuous Post-operative Pulse Oximetry Monitoring in the Obese Patient

Université Libre de Bruxelles

Anesthesia
Completed·Phase 2·ketamine

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)

Bo Hu

Treatment Resistant DepressionElectroconvulsive TherapyECT+6 more
Completed·Phase 3·ketamine

Ketamine and Postoperative Cognitive Dysfunction

Assistance Publique - Hôpitaux de Paris

Post Operative Cognitive Dysfunction
Completed·Phase 1·MDMA

Evaluation of MDMA on Startle Response

Lykos Therapeutics

Startle Response
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.