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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 193240 of 1013 trials
Completed·Phase 1·ketamine

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Celon Pharma SA

Healthy Volunteers
Completed·Phase 1·ketamine

Intravenous Ketamine Plus Neurocognitive Training for Depression

Rebecca Price

Depression
Completed·N/A·ketamine

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, Baltimore

Acute Kidney InjuryRenal InsufficiencyRenal Failure+1 more
Completed·Phase 4·ketamine

Prehospital Analgesia With Intra-Nasal Ketamine

University of British Columbia

PainAcute Pain
Completed·Phase 4·ketamine

Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain

Allevio Pain Management Clinic

Chronic Neuropathic Pain and Fibromyalgia
Completed·Phase 3·ketamine

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

University of Saskatchewan

AnesthesiaGeneral AnesthesiaAnalgesics, Opioid+14 more
Completed·Phase 2·ketamine

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 1·ketamine

A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)

Massachusetts General Hospital

Depression
Completed·Phase 1·ketamine

Ketamine as an Adjunctive Therapy for Major Depression

St Patrick's Hospital, Ireland

Major Depressive EpisodeUnipolar DepressionBipolar Depression
Completed·Phase 4·ketamine

Effect of Ketamine on Analgesia Post-Cardiac Surgery

Jewish General Hospital

Pain, Postoperative
Completed·Phase 4·ketamine

UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study

University of Wisconsin, Madison

UnconsciousnessConsciousness
Completed·N/A·ketamine

Ketamine Versus Midazolam for Prehospital Agitation

Hennepin Healthcare Research Institute

Agitation
Completed·Phase 1·ketamine

Intranasal (NAS) Ketamine for Cancer Pain

Emory University

CancerPain
Completed·Early Phase 1·ketamine

Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

Johns Hopkins University

Lumbar Spinal StenosisLumbar Spinal InstabilityLumbar Spine Degeneration
Completed·N/A·ketamine

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

Avanti Anesthesia

Cataract
Completed·Phase 1·ketamine

Effects of TS-134 on Ketamine-induced BOLD Signals in Healthy Subjects

Taisho Pharmaceutical R&D Inc.

Healthy Volunteers
Completed·Phase 3·ketamine

54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 3·ketamine

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 4·ketamine

The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.

Mayo Clinic

Major DepressionBipolar I DisorderBipolar II Disorder+1 more
Completed·Phase 3·ketamine

Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Chronic Pain
Completed·Phase 2·ketamine

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)

Bo Hu

Treatment Resistant DepressionElectroconvulsive TherapyECT+6 more
Completed·Phase 3·ketamine

Ketamine and Postoperative Cognitive Dysfunction

Assistance Publique - Hôpitaux de Paris

Post Operative Cognitive Dysfunction
Completed·Phase 4·ketamine

Ketamine vs Hydromorphone

University of Florida

Laparoscopic Gastric BypassObesityPain, Postoperative
Completed·Phase 2·ketamine

Pain Free Laceration Repairs Using Intra-nasal Ketamine

Evelyne D.Trottier

Laceration
Completed·Phase 2·ketamine

Ketamine and Nitroprusside for Depression

Icahn School of Medicine at Mount Sinai

Depression
Completed·Phase 4·ketamine

Ketamine Analgesia in Third Molar Surgery

Dalarna County Council, Sweden

PainPostoperative
Completed·Phase 4·ketamine

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients

Turku University Hospital

Pain, Postoperative
Completed·Phase 2·ketamine

Open Label Ketamine Treatment for Major Depressive Disorder in Veterans

VA Connecticut Healthcare System

Major Depressive Disorder
Completed·Phase 2·ketamine

Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain

Hospital de Clinicas de Porto Alegre

Acute PainChronic Pain, WidespreadSchizophrenia
Completed·Phase 4·ketamine

Comparison of Propofol, Propofol-remifentanil and Propofol-ketamine Anesthesia During Electroconvulsive Therapy

Inonu University

AnesthesiaElectroconvulsive Therapy
Completed·Phase 4·ketamine

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

Hospital for Special Surgery, New York

Nerve BlockGeneral AnesthesiaSpinal Anesthesia+2 more
Completed·N/A·ketamine

Cognitive Therapy to Sustain the Antidepressant Effects of Intravenous Ketamine in Treatment-resistant Depression

Yale University

Depressive Disorder, Major
Completed·Early Phase 1·ketamine

Study of Oral Ketamine Versus Placebo for Treating Depression in Patients Undergoing Treatment for Cancer

Scott A. Irwin, MD, PhD

CancerDepression
Completed·N/A·ketamine

Ketamine Infusion Therapy for PTSD in Combat Veterans

Klarisana Physician Services PLLC

Stress Disorders, Post-Traumatic
Completed·Phase 2·ketamine

Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients

The University of Texas Health Science Center, Houston

Treatment Resistant Depression
Completed·Phase 1·ketamine

A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 1·ketamine

Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery

Albert Einstein College of Medicine

AnesthesiaTooth Extraction
Completed·Phase 2·ketamine

Ketamine for Reduction of Alcoholic Relapse

University College, London

Primary Alcohol Use Disorder
Completed·Phase 1·ketamine

A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males

Autifony Therapeutics Limited

Schizophrenia
Completed·Phase 2·ketamine

Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease

University Hospital, Lille

Depression
Completed·Phase 4·ketamine

Intravenous Sub-dissociative Dose Ketamine Injection Versus Infusion for Analgesia in the Emergency Department

Alameda Health System

Pain
Completed·N/A·ketamine

The Effect of Ketamine on the WAVCNS Index During General Anesthesia: A Feasibility Study

Fraser Health

Anesthesia
Completed·Phase 1·ketamine

Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD)

Stanford University

Depression
Completed·Phase 1·ketamine

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly Japanese, and Healthy Younger Adult Japanese Subjects

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D

University of Tennessee

AbscessPain
Completed·Phase 1·ketamine

A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 3·ketamine

Neuroprotection During Open Heart Surgery

ghada fouad

Open Heart Surgery
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.