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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145192 of 1695 trials
Completed·N/A·MDMA

Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD

Albany Research Institute, Inc.

Post Traumatic Stress Disorder
Completed·Phase 3·ketamine

Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient

Assistance Publique Hopitaux De Marseille

Traumatic Injury
Completed·Phase 1·psilocybin

A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder
Completed·Phase 3·Other

Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)

University Hospital, Angers

Pain, PostoperativeCardiac Surgery
Completed·Phase 1·MDMA

Food Effects on Bioavailability of MDMA in Healthy Volunteers

Lykos Therapeutics

Pharmacokinetics
Completed·Phase 4·ketamine

Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

Erika Forbes

DepressionAnhedonia
Completed·Phase 2·ketamine

Ketamine for Treatment-Resistant Bipolar Disorder

Joshua Rosenblat

Bipolar DisorderBipolar DepressionBipolar I Disorder+1 more
Completed·Phase 1·psilocybin

Effects of Psilocybin in Post-Treatment Lyme Disease

Johns Hopkins University

Post-Treatment Lyme DiseaseChronic Lyme DiseaseLyme Disease, Chronic
Completed·Phase 1·psilocybin

An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics

Usona Institute

QTc IntervalPharmacokinetics
Completed·Phase 2·Other

Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)

University of Utah

Hypoxic-Ischemic EncephalopathyPain
Completed·Phase 2·psilocybin

The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

COMPASS Pathways

Post Traumatic Stress Disorder
Completed·N/A·Other

OFA vs OBA in Bariatric Surgery

Hospital HM Nou Delfos

ObesityPostoperative PainBariatric Surgery+1 more
Completed·N/A·Other

Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery

Hospital HM Nou Delfos

Postoperative PainObesityBariatric Surgery+1 more
Completed·Phase 1·ketamine

Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI

Rupert Lanzenberger

Ketamine Treatment
Completed·Early Phase 1·ketamine

Effects of Ketamine on ERP/EEG Measures in Healthy Volunteers

ERP Biomarker Qualification Consortium

Healthy
Completed·Phase 3·Other

Opioid-free Vs Traditional Balanced Anesthesia in Laparoscopic Colorectal Surgery

Unai Ortega Mera

Colorectal Surgery
Completed·Early Phase 1·MDMA

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

University of Chicago

Stimulant UseMDMA ('Ecstasy')Social Behavior+1 more
Completed·Phase 2·ketamine

Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets

University of Texas Southwestern Medical Center

Major Depressive DisorderHealthy Controls
Completed·N/A·ketamine

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

Centre for Addiction and Mental Health

Bipolar Disorder (BD)Suicidality
Completed·Phase 1·LSD

Effects of LSD on Neuroplasticity in Healthy Subjects

University of Fribourg

Healthy
Completed·Phase 3·ketamine

Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial

Washington University School of Medicine

Postoperative Depression
Completed·Phase 2·MDMA

Social Anxiety MDMA-Assisted Therapy Investigation

Jason B Luoma

Social Anxiety Disorder
Completed·N/A·ketamine

Tolerance and Potential Synergistic Effect of the Combination of Intranasal Esketamine and Non-selective MAOI

University Hospital, Strasbourg, France

Depression Anxiety Disorder
Completed·Phase 4·ketamine

Randomized Trial of Sedative Choice for Intubation

Vanderbilt University Medical Center

Acute Respiratory Failure
Completed·N/A·Other

Opioid-free Anesthesia and Thoracoscopy Surgery

Nantes University Hospital

Opioid Free AnesthesiaThoracic Surgery
Completed·N/A·ketamine

Chart Review of Patients Undergoing Ketamine Treatments for Depression

Sunnybrook Health Sciences Centre

Depression - Major Depressive Disorder
Completed·N/A·ketamine

Effect of Ketamine on BIS Values

University of Padova

Anesthesia Brain MonitoringKetamine
Completed·Phase 2·psilocybin

The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

Sheppard Pratt Health System

Treatment Resistant DepressionSuicidal Ideation
Completed·Phase 1·LSD

LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·psilocybin

Evaluation of Psilocybin (TRP-8802) in the Treatment of Binge Eating Disorder

TRYP Therapeutics

Binge Eating Disorder
Completed·Phase 2·psilocybin

Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care

Yvan Beaussant, MD, MSci

HospicePsilocybinDemoralization+5 more
Completed·Phase 3·psilocybin

Frontline Clinician Psilocybin Study

University of Washington

Burnout, CaregiverBurnout, ProfessionalCOVID-19+3 more
Completed·N/A·Other

Venous Cannulation Pain to Guide Choice of Anesthetic Method

Region Halland

Pain, PostoperativePain PredictionLaparoscopic Surgery+2 more
Completed·Phase 1·Other

Single Ascending Dose Study With BPL-003 in Healthy Subjects

Beckley Psytech Limited

Pharmacokinetics in Healthy Adults
Completed·Phase 1·ketamine

Ketamine + Mindfulness for Depression

Rebecca Price

Depression, Unipolar
Completed·Phase 2·ketamine

A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD

Perception Neuroscience

Treatment Resistant Depression
Completed·Phase 2·LSD

Safety and Efficacy of Low Dose MM120 for ADHD Proof of Concept Trial

Definium Therapeutics US, Inc.

ADHDAttention Deficit Disorder
Completed·Phase 1·MDMA

Effects of MDMA-like Substances in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·ketamine

Ketamine for the Treatment of Depression in Parkinson's Disease

Yale University

Parkinson's DiseaseDepression
Completed·Phase 2·psilocybin

Psilocybin for Treatment-Resistant Depression

Brain and Cognition Discovery Foundation

Treatment Resistant Depression
Completed·Phase 3·Other

Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy

Celgene

Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting
Completed·Phase 2·ketamine

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)

Hospices Civils de Lyon

Neuropathic PainComplex Regional Pain Syndrome Type 1
Completed·N/A·MDMA

Stanford Regulating Circuits of the Brain Study - MDMA

Stanford University

Healthy
Completed·N/A·ketamine

Intranasal Ketamine in Ultra-REsistant Depression (SURE-ECT Non Responders)

Centre for Addiction and Mental Health

Depression
Completed·N/A·ketamine

Synaptic Imaging and Network Activity in Treatment Resistant Depression

King's College London

Depressive DisorderDepressive Disorder, MajorDepressive Disorder, Treatment-Resistant+5 more
Completed·N/A·Other

Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry

Novartis

Sickle Cell Disease
Completed·N/A·Other

Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass

matthieu clanet

Analgesics, Opioid
Completed·Early Phase 1·psilocybin

Study of Psilocybin Enhanced Group Psychotherapy in Patients With Cancer

University of Utah

Cancer
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.