CompletedEarly Phase 1MDMA

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

NCT ID

NCT05379959

Target Enrollment

43 participants

Start Date

2022-05-11

Est. Completion

2023-10-24

About This Study

To study the effects of MDMA, compared to a prototypical stimulant, on social motivation, social ability, and neural indices of social function in healthy volunteers

Conditions Studied

Stimulant UseMDMA ('Ecstasy')Social BehaviorMotivation

Interventions

•MDMA
•Methamphetamine
•placebo oral tablet

Eligibility

Age:18 Years - 40 Years

Healthy Volunteers:Yes

View full eligibility criteria

Inclusion Criteria:

* BMI between 19 and 30 (no one under 130 lbs)
* Smokers smoking less than 25 cigarettes per week
* Have used ecstasy no more than 40 times with no adverse responses.

Exclusion Criteria:

* High blood pressure
* Any medical condition requiring regular medication
* Individuals with a current (within the last year) DSM-IV Axis 1 diagnosis
* Individuals with a history of dependence on stimulant drugs.
* Women who are pregnant or trying to become pregnant

Study Locations (1)

University of Chicago