Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Intravenous Ketamine for Treatment-Resistant Depression
Mayo Clinic
MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder
Patricia Suppes
Investigation of Psychedelic Effects in Psychoactive Substances
Johns Hopkins University
Non-steroidal Anti-inflammatory Drugs in Pleurodesis
Centre Hospitalier Universitaire, Amiens
State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
Baylor College of Medicine
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
Definium Therapeutics US, Inc.
The ENHANCE Study: taVNS and Psilocybin
University of Wisconsin, Madison
Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls
University Hospital, Basel, Switzerland
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
Yale University
Pragmatic Trial of Psilocybin Therapy in Palliative Care
Charles S. Grob, M.D.
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
University of California, San Diego
Psilocybin rTMS for Treatment Resistant Depression
University of Texas at Austin
Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression
Icahn School of Medicine at Mount Sinai
Psychedelic-assisted Group Program for First Responders
Empower Research Inc
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
Cybin IRL Limited
Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Unity Health Toronto
Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest
Christian Hassager
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)
Definium Therapeutics US, Inc.
Safety for Home Administration of Microdose Psilocybin Use
Johns Hopkins University
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Insel Gruppe AG, University Hospital Bern
Modulation of the Inflammatory Response in Bariatric Surgery
Hospital HM Nou Delfos
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
University of Colorado, Denver
Study of Psilocybin for Anorexia in Young Adults
Marissa Raymond-Flesch, MD, MPH
MDMA-Assisted CBCT for PTSD vs CBCT RCT
Remedy
Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life
Albany Research Institute, Inc.
Psilocybin-assisted Treatment for Cannabis Use Disorder
Johns Hopkins University
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
National Institute of Mental Health (NIMH)
Psilocybin for Treatment-Resistant Depression in Autism
Centre for Addiction and Mental Health
A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis
Novartis Pharmaceuticals
MDMA-assisted Massed Prolonged Exposure for PTSD
Healing Breakthrough
Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers
Robin Carhart-Harris, PhD, MA
Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients
Assistance Publique - Hôpitaux de Paris
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting
Theresa Jacob, PhD, MPH
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
University Health Network, Toronto
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils
Oregon Health and Science University
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
At-Home tDCS as Maintenance Therapy
Technical University of Munich
Psilocybin in Cancer Pain Study
Yvan Beaussant, MD, MSci
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
Rush University Medical Center
Ketamine for Methamphetamine Use Disorder
University of Texas Southwestern Medical Center
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
Sharmin Ghaznavi
Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD
Centre for Addiction and Mental Health
Imaging Depression in Parkinson's Disease
Yale University
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Dr. Inge Winter
Psilocybin Therapy for Depression in Parkinson's Disease
Joshua Woolley, MD, PhD
Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy Subjects
GH Research Ireland Limited
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.