Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Comparative Acute Effects of R-MDMA and S-MDMA in Healthy Participants
University Hospital, Basel, Switzerland
Magnesium and Cramping
Corewell Health East
A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression
Juliana Zambrano, MD, MPH
Ketamine Augmentation of ECT in Treatment-Resistant Depression
Università Vita-Salute San Raffaele
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients
Mayo Clinic
Ketamine, SGB and Combination Treatment for TBI
Northwestern University
Reducing Pain With Methadone and Ketamine in Liver Transplant
Lahey Clinic
Drug Effects on Mood and Behavior - Expectancy
University of Chicago
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Mood Effects of Serotonin Agonists: Depression
University of Chicago
Dose Optimization of MDMA-Assisted Therapy for PTSD
Bronx VA Medical Center
Music as an Adjunct to Ketamine Therapy for Chronic Pain
McGill University
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
Dr. med. Marcus Herdener
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
Neuronetics
Investigation to Understand and Optimize Psilocybin
Charles Raison
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
Queen's University
ESKetamine Low-dose vs Ketamine Low-dose for Severe Acute Pain in Emergency Units, Comparison of PsychodyslEptic Effects
Centre Hospitalier Universitaire de Nice
ACT_for Alcohol Use Disorder and Depression
Centre hospitalier de l'Université de Montréal (CHUM)
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Centre for Addiction and Mental Health
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
Psilocybin Brain Stimulation and Imaging Pilot Study
Johns Hopkins University
LSD to Improve Cluster Headache Impact Trial
Radboud University Medical Center
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
Nantes University Hospital
Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)
University of Twente
Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
Johns Hopkins University
Understanding and Treating Suicidal Ideation With Ketamine
The Royal's Institute of Mental Health Research
Psilocybin for Methamphetamine Addiction
Kevin Murnane
Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects
University Hospital, Basel, Switzerland
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
University Hospital, Basel, Switzerland
Tolerability of MDMA in Schizophrenia
Anya Bershad, MD, PhD
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
Grace Lim, MD, MS
Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers
MoCA Clinic and Institute
Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans
Deepak C. D'Souza
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV
Nicky Mehtani, MD, MPH
Digital Intervention for Psychedelic Preparation (DIPP): Comparing Meditation and Music-Based Programs
University College, London
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
McMaster University
Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine
Assistance Publique - Hôpitaux de Paris
Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
Icahn School of Medicine at Mount Sinai
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.