181 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 4996 of 1013 trials
Completed·Phase 2·ketamine

Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001

Cessatech A/S

Pain
Completed·Phase 2·ketamine

Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression

Joshua Rosenblat

Bipolar DisorderBipolar DepressionBipolar I Disorder+1 more
Completed·Phase 3·ketamine

Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient

Assistance Publique Hopitaux De Marseille

Traumatic Injury
Completed·Phase 4·ketamine

Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

Erika Forbes

DepressionAnhedonia
Completed·Phase 2·ketamine

Ketamine for Treatment-Resistant Bipolar Disorder

Joshua Rosenblat

Bipolar DisorderBipolar DepressionBipolar I Disorder+1 more
Completed·Phase 1·ketamine

Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI

Rupert Lanzenberger

Ketamine Treatment
Completed·Early Phase 1·ketamine

Effects of Ketamine on ERP/EEG Measures in Healthy Volunteers

ERP Biomarker Qualification Consortium

Healthy
Completed·Phase 2·ketamine

Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets

University of Texas Southwestern Medical Center

Major Depressive DisorderHealthy Controls
Completed·N/A·ketamine

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

Centre for Addiction and Mental Health

Bipolar Disorder (BD)Suicidality
Completed·Phase 3·ketamine

Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial

Washington University School of Medicine

Postoperative Depression
Completed·N/A·ketamine

Tolerance and Potential Synergistic Effect of the Combination of Intranasal Esketamine and Non-selective MAOI

University Hospital, Strasbourg, France

Depression Anxiety Disorder
Completed·Phase 4·ketamine

Randomized Trial of Sedative Choice for Intubation

Vanderbilt University Medical Center

Acute Respiratory Failure
Completed·N/A·ketamine

Chart Review of Patients Undergoing Ketamine Treatments for Depression

Sunnybrook Health Sciences Centre

Depression - Major Depressive Disorder
Completed·N/A·ketamine

Effect of Ketamine on BIS Values

University of Padova

Anesthesia Brain MonitoringKetamine
Completed·Phase 1·ketamine

Ketamine + Mindfulness for Depression

Rebecca Price

Depression, Unipolar
Completed·Phase 2·ketamine

A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD

Perception Neuroscience

Treatment Resistant Depression
Completed·Phase 2·ketamine

Ketamine for the Treatment of Depression in Parkinson's Disease

Yale University

Parkinson's DiseaseDepression
Completed·Phase 2·ketamine

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)

Hospices Civils de Lyon

Neuropathic PainComplex Regional Pain Syndrome Type 1
Completed·N/A·ketamine

Intranasal Ketamine in Ultra-REsistant Depression (SURE-ECT Non Responders)

Centre for Addiction and Mental Health

Depression
Completed·N/A·ketamine

Synaptic Imaging and Network Activity in Treatment Resistant Depression

King's College London

Depressive DisorderDepressive Disorder, MajorDepressive Disorder, Treatment-Resistant+5 more
Completed·Phase 4·ketamine

Comparison of Nebulized Ketamine to Intravenous Sub-Dissociative Dose Ketamine for Pain

Antonios Likourezos

Pain
Completed·Phase 4·ketamine

Low Dose Ketamine for Blunt Thoracic Trauma

North Memorial Health Care

Blunt Injury of ThoraxMultiple Rib Fractures, Involving Three Ribs
Completed·Early Phase 1·ketamine

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

King's College London

Depressive Disorder, Treatment-Resistant
Completed·Phase 1·ketamine

Study of SAGE-904 Using a Ketamine Challenge to Evaluate Electrophysiology, Safety, Tolerability, and Pharmacokinetics in Healthy Participants

Supernus Pharmaceuticals, Inc.

Healthy Volunteer
Completed·Phase 1·ketamine

Repeated Neurocognitive Measurements in Depressed Patients

Rebecca Price

Depression, Unipolar
Completed·Phase 3·ketamine

Ketamine As an Adjunctive Therapy for Major Depression (2)

University of Dublin, Trinity College

Major Depressive EpisodeUnipolar DepressionBipolar Depression
Completed·N/A·ketamine

Simultaneous Application of Ketamine and Lidocaine During an Ambulatory Infusion Therapy as a Treatment Option in Refractory Chronic Pain Conditions

University Hospital, Basel, Switzerland

Chronic Pain
Completed·Phase 1·ketamine

A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue

National Institute of Nursing Research (NINR)

Fatigue
Completed·Phase 2·ketamine

A Study of MELT-300 (Midazolam and Ketamine Sublingual Tablets) for Sedation and Intraoperative Ocular Analgesia in Participants Undergoing Cataract Extraction With Lens Replacement (CELR)

Melt Pharmaceuticals

Cataract
Completed·Phase 2·ketamine

The Effect of Opioid-Free Anesthesia in TMJ Surgery

Massachusetts General Hospital

Temporomandibular Joint Disorders
Completed·Phase 2·ketamine

Adding Trauma-focused Psychotherapy to Ketamine Treatment for Chronic PTSD

Icahn School of Medicine at Mount Sinai

PTSD
Completed·Phase 4·ketamine

Ketamine Versus Fentanyl for Surgical Abortions

University of Washington

Abortion in First TrimesterPain, ProceduralOpioid Use
Completed·Phase 4·ketamine

Effect of Postoperative Single Dose of Ketamine on Pain After Mastectomy

NYU Langone Health

Postoperative Pain
Completed·Phase 4·ketamine

A Long-Term Extension Study for Participants With Treatment-resistant Major Depressive Disorder Who Are Continuing Esketamine Nasal Spray Treatment

Janssen-Cilag Ltd.

Depressive Disorder, Major
Completed·Phase 4·ketamine

A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain

Antonios Likourezos

Pain
Completed·Phase 4·ketamine

An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache

Antonios Likourezos

Pain
Completed·Phase 4·ketamine

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Vanderbilt University Medical Center

Opioid UseEnhanced Recovery After SurgeryAnesthesia+2 more
Completed·Phase 1·ketamine

Modified Ketogenic Diet and Ketamine for Anorexia Nervosa

Homeostasis Therapeutics, LLC

Anorexia Nervosa
Completed·Phase 1·ketamine

Study of CT001 in Healthy Volunteers

Cessatech A/S

Bioavailability
Completed·Phase 2·ketamine

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

VA Office of Research and Development

PTSD
Completed·N/A·ketamine

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention

Yale University

Depression and Suicide
Completed·N/A·ketamine

Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC

Centre Leon Berard

CancerChronic PainNeuropathic Pain+1 more
Completed·N/A·ketamine

Pharmacogenetics Associated With IV Ketamine

Brain and Cognition Discovery Foundation

Treatment Resistant Depression
Completed·N/A·ketamine

Ketamine for Pain Control After Severe Traumatic Injury

Medical College of Wisconsin

Hospital Inpatient Trauma InjuryPain Management
Completed·Early Phase 1·ketamine

Inpatient Single Dose Interventions for Alcohol Use Disorder

Denver Health and Hospital Authority

Alcohol Use Disorder, Severe
Completed·Phase 1·ketamine

Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine

National Institute of Mental Health (NIMH)

Major Depressive Disorder
Completed·N/A·ketamine

Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression

Douglas Mental Health University Institute

Depressive Disorder, Treatment-ResistantDepressive Disorder, MajorUnipolar Depression+1 more
Completed·N/A·ketamine

Analgesic Efficacy of Orally Administered VTS-K for Pain Management

Antonios Likourezos

Pain, Acute
PreviousPage 2 of 22Next

Browse by Condition

View all conditions →

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.