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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 721768 of 1013 trials
Terminated·Phase 2·ketamine

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression

Zylorion Health

Treatment Resistant Major Depressive Disorder
Terminated·Phase 4·ketamine

Ketamine Pilot Study

Meghan Spyres

Rattlesnake Envenomation
Terminated·Phase 1·ketamine

Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics

University of British Columbia

Suicidal Ideation
Terminated·Phase 4·ketamine

Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED

University of Aarhus

Acute PainOpioid Use
Terminated·Phase 1·ketamine

The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study

NYU Langone Health

EndometriosisPost Operative Pain
Terminated·Phase 1·ketamine

Ketamine for OUD and Comorbid Depression (OUDCD)

University of Maryland, Baltimore

Opioid Use DisorderDepressive Disorder
Terminated·Phase 2·ketamine

Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine

Yale University

Adolescent SuicideAdolescent Depression
Terminated·Phase 2·ketamine

KAP for Depression in Abstinent Opioid Users

Medical University of South Carolina

Opioid Use Disorder, Severe, in Sustained RemissionOpioid Use Disorder, Severe, in Early RemissionMajor Depressive Disorder
Terminated·N/A·ketamine

Effect of Ketamine on Neurological Activity as Measured by Electroencephalogram (EEG)

Entheon Biomedical Corp.

Treatment-resistant Depression
Terminated·Early Phase 1·ketamine

Ketamine in Veterans With Gulf War Illness

Baylor College of Medicine

Gulf War Syndrome
Terminated·Phase 1·ketamine

The Effects of Low Dose Ketamine on Cardiovascular Function

University of Texas Southwestern Medical Center

Healthy
Terminated·N/A·ketamine

ESKETamine for FIBromyalgia Treatment

Grand Hôpital de Charleroi

Fibromyalgia
Terminated·Early Phase 1·ketamine

PVB vs Ketamine/Lidocaine in Rib Fracture Patients

George Washington University

Rib FracturesRib TraumaRib Fracture Multiple+1 more
Terminated·Phase 2·ketamine

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19

Corewell Health East

COVID-19Acute Respiratory Distress SyndromeSevere Acute Respiratory Syndrome (SARS)+1 more
Terminated·Phase 3·ketamine

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Case Comprehensive Cancer Center

Postoperative Pain ControlOpioid Consumption
Terminated·Phase 3·ketamine

Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department

Naval Medical Center Camp Lejeune

SuicideSuicide ThreatDepression Severe
Terminated·Phase 1·ketamine

Ketamine Interleaved With Electroconvulsive Therapy for Depression

St Patrick's Hospital, Ireland

Depression
Terminated·Phase 3·ketamine

Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED

Abigail Nixon

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseVaso-occlusive Crisis+3 more
Terminated·Phase 4·ketamine

Ketamine + Cognitive Training for Suicidality in the Medical Setting: Pilot

Rebecca Price

Suicide, Attempted
Terminated·Phase 2·ketamine

Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery

Jacques E. Chelly

Opioid DependenceChronic Pain
Terminated·Phase 4·ketamine

Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain

Mercy Health Ohio

Pain, Acute
Terminated·Phase 4·ketamine

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

University of Alabama at Birmingham

TraumaFractures, ClosedChildren, Only+2 more
Terminated·Phase 2·ketamine

Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy

Yale University

Major Depressive Disorder
Terminated·Phase 1·ketamine

The Role of HNKs in the Antidepressant Effect of Ketamine

Columbia University

Major Depressive Disorder
Terminated·Phase 4·ketamine

Ketamine for Pain in the Emergency Department

Hackensack Meridian Health

Acute Pain
Terminated·Phase 2·ketamine

Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression

The University of Texas Health Science Center, Houston

Post Partum Depression
Terminated·Phase 1·ketamine

Acute Pain Management in Patients on Opioid Replacement Therapy

University of California, San Francisco

Opioid-use DisorderPain, Acute
Terminated·Phase 4·ketamine

IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair

Corewell Health East

Laceration of Skin
Terminated·Phase 2·ketamine

Ketamine in Borderline Personality Disorder

Yale University

Borderline Personality Disorder
Terminated·Phase 4·ketamine

RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain

Johns Hopkins University

Acute PainWound CarePosttraumatic Stress Disorder
Terminated·Phase 3·ketamine

Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia

Nantes University Hospital

Pain Management
Terminated·Early Phase 1·ketamine

Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study

University of Arizona

Failed Moderate Sedation During ProcedureKetamine Adverse Reaction
Terminated·Phase 4·ketamine

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

Montefiore Medical Center

Pain, Postoperative
Terminated·Phase 1·ketamine

Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids

Milton S. Hershey Medical Center

Chronic Pain
Terminated·Phase 2·ketamine

Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine

Gil Yosipovitch

Pruritus
Terminated·Phase 4·ketamine

Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients

Emory University

Otolaryngeal Cancer
Terminated·Phase 4·ketamine

The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.

Allen Richert

Suicidal Ideation
Terminated·Phase 2·ketamine

The UTHealth Ketamine Project

The University of Texas Health Science Center, Houston

Treatment Resistant DepressionMajor Depressive DisorderBipolar Disorder
Terminated·Phase 3·ketamine

The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine

Mike O'Callaghan Military Hospital

Headache
Terminated·Phase 4·ketamine

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

Virginia Commonwealth University

Heart Diseases
Terminated·N/A·ketamine

Physiological and Cognitive Biomarkers for Ketamine's Antidepressant Effects

Massachusetts General Hospital

Depression
Terminated·Phase 2·ketamine

Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea

University of Alabama at Birmingham

Sleep ApneaObstructive Sleep ApneaPostoperative Complications
Terminated·Phase 4·ketamine

Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients

Brooke Army Medical Center

AnxietyPediatric ALLProcedural Anxiety
Terminated·Phase 4·ketamine

Ketamine and Refractory Painful Care in a Palliative Unit

Lille Catholic University

Intractable PainIntensive CarePressure Ulcer+1 more
Terminated·Phase 4·ketamine

Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy

Icahn School of Medicine at Mount Sinai

ObesityBariatricsSleep Apnea Syndromes+2 more
Terminated·N/A·ketamine

Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms

The University of Texas Health Science Center at San Antonio

DepressionMajor Depressive Disorder
Terminated·Phase 2·ketamine

Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy

Yale University

Posttraumatic Stress Disorder
Terminated·Phase 1·ketamine

Ketamine for Relapse Prevention in Recurrent Depressive Disorder

St Patrick's Hospital, Ireland

DepressionRelapseRecurrent Depressive Disorder+1 more
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.