TerminatedPhase 4ketamine

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

NCT ID

NCT02734940

Target Enrollment

3 participants

Start Date

2016-07-11

Est. Completion

2017-02-01

About This Study

The investigators objective is to assess the effectiveness of an opioid sparing multimodal approach for enhancing the recovery in Cardiac Surgical patients. This model would use a combination of intravenous (Dexmedetomidine, Ketamine, Lidocaine) and Spinal (Morphine) drugs.

Conditions Studied

Heart Diseases

Interventions

•Lidocaine
•Unrestricted Fentanyl
•Ketamine
•Precedex
•Duramorph

Eligibility

Age:18 Years - N/A

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Elective CABGs and/or Valve replacements, ≥ 18 years old

Exclusion Criteria:

* Re-do cardiac surgery, Acute endocarditis, Circulatory arrest, Emergent cases, Shock, Left Ventricular Assist Device, Transplantation, Transcatheter Aortic Valve Replacement, contraindications for Spinal including coagulopathy and Clopidogrel \<7days, psychosis, known allergy to any of the study drugs, Preoperative liver dysfunction (AST/ALT \> 2 times normal) and Renal dysfunction (Cr \> 2 mg/dL), inability to administer spinal anesthetic, preoperative opioid use, patients who are unable to give their own consent, expected prolonged intubation postoperatively (\>12 hrs), prisoners, pregnancy

Study Locations (1)

Virginia Commonwealth University

Richmond, Virginia, United States