24 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 58 of 58 trials
Completed·N/A·ketamine

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention

Yale University

Depression and Suicide
Completed·Phase 2·ketamine

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Major Depressive Disorder
Recruiting·Phase 4·ketamine

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Major Depressive Disorder
Unknown·Phase 3·ketamine

The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression

Tel-Aviv Sourasky Medical Center

Suicidal IdeationMajor Depressive DisorderHealthy Participants
Recruiting·Phase 2·ketamine

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Yale University

Depressive DisorderMajor Depressive DisorderBipolar Disorder+2 more
Completed·N/A·ketamine

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

Centre for Addiction and Mental Health

Bipolar Disorder (BD)Suicidality
Completed·Phase 4·ketamine

Ketamine in the Treatment of Suicidal Depression

New York State Psychiatric Institute

Major Depressive DisorderSuicidal Ideation
Completed·Phase 4·ketamine

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

MercyOne Des Moines Medical Center

DepressionDepression SevereDepression Acute+2 more
Unknown·Early Phase 1·ketamine

Ketamine for Mood Disorders With Suicidal Ideation

The Miriam Hospital

Depressive Disorder, MajorSuicidal Ideation
Not Yet Recruiting·Phase 3·ketamine

Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents

Federal University of São Paulo

Depressive DisorderSuicidal Ideas
Withdrawn·Phase 3·ketamine

The Impact of Ketamine on the Reward Circuitry of Suicidal Patients

Massachusetts General Hospital

Suicidal IdeationSuicide
Unknown·Phase 2·ketamine

Emergency Ketamine Treatment of Suicidal Ideation

University of Cincinnati

DepressionSuicidal IdeationSuicidal Impulses
Completed·Phase 2·ketamine

Ketamine for Depression and Suicide Risk

Mayo Clinic

DepressionSuicide
Completed·N/A·Other

2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and Policy Recommendation

Dr.Yoav Domany

Treatment Resistant Depression (TRD)Depression - Major Depressive DisorderBipolar Depression
Terminated·Phase 1·ketamine

Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics

University of British Columbia

Suicidal Ideation
Recruiting·Phase 2·psilocybin

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

The University of Texas Health Science Center, Houston

Bipolar II DisorderDepression, BipolarSuicidality
Completed·Phase 3·ketamine

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Terminated·Phase 4·ketamine

The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.

Allen Richert

Suicidal Ideation
Completed·Phase 4·ketamine

Ketamine Infusion for Adolescent Depression and Anxiety

Yale University

Major Depressive DisorderAnxiety Disorder
Completed·Phase 2·ketamine

miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome

University of Alabama at Birmingham

Major Depressive Disorder
Terminated·Phase 4·ketamine

Ketamine + Cognitive Training for Suicidality in the Medical Setting: Pilot

Rebecca Price

Suicide, Attempted
Completed·Phase 3·ketamine

Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents

University of Texas Southwestern Medical Center

Suicide, AttemptedSuicide and DepressionSuicide Threat
Completed·Phase 2·psilocybin

The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

Sheppard Pratt Health System

Treatment Resistant DepressionSuicidal Ideation
Withdrawn·Phase 4·ketamine

Intranasal Ketamine for Late-Life Depression and Suicidal Ideation

Massachusetts General Hospital

DepressionSuicideSuicidal Ideation
Recruiting·N/A·ketamine

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation

Children's Hospital of Eastern Ontario

Suicidal IdeationSuicidal Ideas
Unknown·Phase 3·ketamine

NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression

NeuroRx, Inc.

Bipolar DepressionSuicidal Ideation
Completed·N/A·ketamine

Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality

Assiut University

Treatment Resistant Depression
Recruiting·Phase 2·ketamine

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The University of Texas Health Science Center at San Antonio

Suicide
Not Yet Recruiting·Phase 4·ketamine

Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts

New York State Psychiatric Institute

Major Depressive Disorder (MDD)
Recruiting·Phase 1·ketamine

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Lindsay Maguire, MD

SuicideSuicidal IdeationDepression
Unknown·Early Phase 1·ketamine

Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department

Rady Children's Hospital, San Diego

DepressionSuicidal Ideation
Unknown·Phase 3·ketamine

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation

University of Ottawa

Suicidal Ideation
Recruiting·Phase 2·ketamine

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Characteristics of (R)-Ketamine Hydrochloride Nasal Spray in Patients With Depression and Acute Suicidal Ideation or Behavior

Sichuan Purity Pharmaceutical Technology Co., Ltd.

Major Depressive Disorder (MDD
Enrolling by Invitation·N/A·ketamine

Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation

University of California, San Diego

Suicidal Ideation
Withdrawn·Phase 2·ketamine

Intramuscular Ketamine for Suicidal Ideation

Icahn School of Medicine at Mount Sinai

Suicidal Ideation
Unknown·N/A·ketamine

Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial

Brooke Army Medical Center

Suicide
Active, Not Recruiting·Phase 4·ketamine

Ketamine + Cognitive Training for Suicidality in the Medical Setting

Rebecca Price

Suicide, Attempted
Completed·Early Phase 1·ketamine

Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression.

Sunnybrook Health Sciences Centre

Major Depressive DisorderBipolar I DisorderBipolar II Disorder+2 more
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 2·ketamine

Sequential Therapy for the Treatment of Severe Bipolar Depression.

NeuroRx, Inc.

Bipolar DepressionSuicidal IdeasSuicidal Ideation+1 more
Recruiting·Phase 2·ketamine

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

University Health Network, Toronto

Major Depressive DisorderSuicideTreatment Resistant Depression
Terminated·Phase 2·ketamine

Ketamine for OUD and Suicidal Ideation in the ED

Brigham and Women's Hospital

Opioid Use DisorderSuicidal Ideation
Completed·Phase 3·ketamine

Effects of Ketamine in the Acute Phase of Suicidal Ideation

Centre Hospitalier Universitaire de Nīmes

Suicidal Ideation
Completed·Phase 2·ketamine

A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide

Seelos Therapeutics, Inc.

Depressive Disorder, MajorSuicidal
Completed·N/A·ketamine

Treatment of Suicidal Ideation With Intravenous Ketamine Infusion

University of Alabama at Birmingham

DepressionSuicidal Ideation
Suspended·Phase 4·ketamine

IM Ketamine vs Midazolam for Suicidal ER Patients

New York State Psychiatric Institute

Depression, UnipolarDepression, BipolarSuicidal Ideation
Completed·Phase 4·ketamine

Ketamine For Suicidal Ideation

James Murrough

Suicidal Ideation
Completed·Phase 1·ketamine

Ketamine for Suicidality in Bipolar Depression

New York State Psychiatric Institute

Bipolar DisorderMajor Depressive EpisodeSuicidal Ideation
Withdrawn·Phase 2·ketamine

ED Treatment of Suicidal Patients With Ketamine Infusion

University of California, Davis

SuicideSuicidal Ideation
Completed·N/A·ketamine

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Completed·Phase 3·ketamine

Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse

The University of Texas Health Science Center, Houston

Suicidal IdeationDepressionAlcohol Abuse
Completed·N/A·ketamine

Sustained Ketamine Effectiveness for Suicidal Ideation

University Hospital, Montpellier

Depression - Major Depressive DisorderSuicide
Completed·Phase 3·ketamine

54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major
Unknown·Phase 2·ketamine

A Single Ketamine Infusion Combined With Music for Suicidal Ideation

The University of Texas Health Science Center at Tyler

Suicidal IdeationDepressive Episode
Recruiting·Phase 2·ketamine

Understanding and Treating Suicidal Ideation With Ketamine

The Royal's Institute of Mental Health Research

Suicidal IdeationMajor Depressive Disorder (MDD)
Withdrawn·Early Phase 1·ketamine

Intranasal Ketamine for Suicidal Ideation in Veterans

Bronx Veterans Medical Research Foundation, Inc

Suicidal Ideation
Completed·N/A·ketamine

Esketamine vs ECT for Acute Suicidality

Capital Medical University

Mood DisordersSuicidal IdeationDepressive Episode
Completed·Phase 2·ketamine

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Depressive Disorder, Major

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.