Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Psilocybin-assisted Treatment for Cannabis Use Disorder
Johns Hopkins University
Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
VA Office of Research and Development
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
International Center for Ethnobotanical Education, Research, and Service
Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
Johns Hopkins University
Ketamine Assisted Psychotherapy for Opioid Use Disorder
University of Utah
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Personality and Drug Use
Psychedelic Data Society
MDMA for AUD/PTSD Comorbidity
Carolina L Haass-Koffler
Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers
National Taiwan University
Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
VA Connecticut Healthcare System
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
The Effects of Sedatives on Tobacco Use Disorder
Wake Forest University Health Sciences
LSD Treatment for Persons With Alcohol Use Disorder
Felix Mueller
ACT_for Alcohol Use Disorder and Depression
Centre hospitalier de l'Université de Montréal (CHUM)
Psilocybin for Opioid Use Disorder (OUD)
NYU Langone Health
Opioid Free Anesthesia vs. Opioid Anesthesia Techniques.
University of South Florida
Ketamine for Methamphetamine Use Disorder
University of Texas Southwestern Medical Center
Ketamine for OUD and Comorbid Depression (OUDCD)
University of Maryland, Baltimore
A Study of Oral Ibogaine in Opioid Withdrawal
atai Therapeutics, Inc.
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
Substance Misuse To Psychosis for Ketamine (SToP-K)
The University of Hong Kong
The Effects of Sedatives on Tobacco Use Disorder Version 2
Wake Forest University Health Sciences
Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
Johns Hopkins University
Psilocybin on Brain Mechanisms of Motivation in OUD
Anna Rose Childress, Ph.D.
Psilocybin-facilitated Treatment for Cocaine Use
University of Alabama at Birmingham
Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction
Dr. med. Marcus Herdener
Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility Study
Anders Fink-Jensen, MD, DMSci
Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder
Peggy C Nopoulos
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
Johns Hopkins University
Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder
Brugmann University Hospital
Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
University Hospital, Geneva
MDMA for Co-occurring PTSD and OUD After Childbirth
University of New Mexico
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
Psilocybin-assisted Therapy for Alcohol Use Disorder
University of Sydney
Psilocybin-Enhanced Psychotherapy for Methamphetamine Use Disorder
Portland VA Research Foundation, Inc
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
University of California, Irvine
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
Abuse Potential and Human Pharmacology of Methylone
Germans Trias i Pujol Hospital
Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)
South West Sydney Local Health District
Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder
Johns Hopkins University
Transition From Acute to Chronic Opioid Use and Chronic Pain
Jacques E. Chelly
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder
Johns Hopkins University
Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.
California Pacific Medical Center Research Institute
Inpatient Single Dose Interventions for Alcohol Use Disorder
Denver Health and Hospital Authority
MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder
University of Sydney
Ketamine for Combined Depression and Alcohol Use Disorder
University Hospital of North Norway
Personality and Drug Use (PDU)
Quantified Citizen Technologies Inc.
Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism
Healing Advocacy Fund
Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder
University of Wisconsin, Madison
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Yale University
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
Ketamine for OUD and Suicidal Ideation in the ED
Brigham and Women's Hospital
Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine
University of Wisconsin, Madison
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)
Clairvoyant Therapeutics
Bristol Imperial MDMA in Alcoholism Study
Imperial College London
Ketamine for the Treatment of Opioid Use Disorder and Depression
Medical University of South Carolina
KAP for Depression in Abstinent Opioid Users
Medical University of South Carolina
Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
University of Zurich
Psilocybin in Alcohol Use Disorder With Comorbid Depression
Centre Hospitalier Universitaire de Nīmes
Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use
Johns Hopkins University
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
Dr. med. Marcus Herdener
Acute Pain Management in Patients on Opioid Replacement Therapy
University of California, San Francisco
Ketamine for Opioid Use Disorder
University of Maryland, Baltimore
Wellcome Leap Psilocybin for OUD
Anna Rose Childress, Ph.D.
Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population
Hospices Civils de Lyon
Ketamine for the Treatment for Alcohol Use Disorder in the ED
Brigham and Women's Hospital
Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Keith Heinzerling
Psilocybin for Methamphetamine Addiction
Kevin Murnane
Addiction in Intensive Cardiac Care Units
Assistance Publique - Hôpitaux de Paris
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
VA Office of Research and Development
Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder
University of Calgary
Psilocybin-assisted Therapy for Treatment of Alcohol Use Disorder
Anders Fink-Jensen, MD, DMSci
Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder
Medical University of South Carolina
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
Read the trial details, eligibility criteria, and what participation involves.
Reach out to the study team using the contact information provided.
Complete the screening process to determine if you're eligible.