24 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 40 of 40 trials
Terminated·Phase 4·ketamine

Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED

University of Aarhus

Acute PainOpioid Use
Completed·Phase 2·ibogaine

Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification

International Center for Ethnobotanical Education, Research, and Service

Drug DependenceDrug Use DisordersOpioid Dependence
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Opioid Use Disorder

University of Utah

Opioid-use Disorder
Not Yet Recruiting·Phase 2·ketamine

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

University of California, San Diego

Opioid Use Disorder
Completed·N/A·ketamine

Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC

Centre Leon Berard

CancerChronic PainNeuropathic Pain+1 more
Recruiting·N/A·Other

Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids

G.Gennimatas General Hospital

Opioid Use, UnspecifiedBariatric Surgery Candidate
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Unknown·Phase 2·Other

Opioid Free Anesthesia vs. Opioid Anesthesia Techniques.

University of South Florida

Analgesic Drug DependenceColectomy
Completed·Phase 4·ketamine

Use of Ketamine Associate With an Opioid for Sedation in ICU

University Hospital, Clermont-Ferrand

Sedation for Mechanical Ventilation
Terminated·Phase 1·ketamine

Ketamine for OUD and Comorbid Depression (OUDCD)

University of Maryland, Baltimore

Opioid Use DisorderDepressive Disorder
Completed·Phase 1·ibogaine

A Study of Oral Ibogaine in Opioid Withdrawal

atai Therapeutics, Inc.

Opiate Withdrawal Syndrome
Recruiting·N/A·psilocybin

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Recruiting·Phase 2·psilocybin

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

University of British Columbia

Opioid DependenceChronic Pain
Unknown·Phase 4·Other

Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric Surgery

Tanta University

AnesthesiaHypoventilationOpioid Use+1 more
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Completed·N/A·Other

Opioid Free Anesthesia and Major Spine Surgery

Lebanese American University

Opioid UsePostoperative PainSpine Disease
Recruiting·Phase 2·MDMA

MDMA for Co-occurring PTSD and OUD After Childbirth

University of New Mexico

Stress Disorders, Post-TraumaticOpioid Use Disorder
Recruiting·Phase 4·Other

Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC

University of Crete

Systemic Inflammatory Response SyndromePostoperative Pain, AcutePostoperative Pain, Chronic+4 more
Recruiting·Phase 1·psilocybin

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Yale University

Opioid Use Disorder
Recruiting·N/A·ibogaine

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

University of California, Irvine

Opioid Use Disorder (OUD)
Recruiting·Phase 3·ketamine

Oral Ketamine for Treatment of Vaso-Occlusive Pain

Boston Children's Hospital

Vaso-occlusive Crisis
Recruiting·Phase 4·ketamine

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Recruiting·Phase 2·psilocybin

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Not Yet Recruiting·Early Phase 1·Other

Transition From Acute to Chronic Opioid Use and Chronic Pain

Jacques E. Chelly

Opioid Use Disorder
Completed·Phase 2·ketamine

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

Grace Lim, MD, MS

Obstetric PainPostpartum DepressionBreastfeeding+5 more
Suspended·Phase 2·psilocybin

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Terminated·Phase 2·ketamine

Ketamine for OUD and Suicidal Ideation in the ED

Brigham and Women's Hospital

Opioid Use DisorderSuicidal Ideation
Completed·Phase 4·ketamine

Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy

Medical University of Warsaw

ObesityPostoperative PainPostoperative Nausea+2 more
Recruiting·Phase 1·psilocybin

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

University of Wisconsin, Madison

Opioid Use Disorder
Completed·Early Phase 1·ketamine

Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

Johns Hopkins University

Lumbar Spinal StenosisLumbar Spinal InstabilityLumbar Spine Degeneration
Completed·Phase 2·ketamine

Ketamine for the Treatment of Opioid Use Disorder and Depression

Medical University of South Carolina

DepressionOpioid-use DisorderOpioid Abuse
Terminated·Phase 2·ketamine

KAP for Depression in Abstinent Opioid Users

Medical University of South Carolina

Opioid Use Disorder, Severe, in Sustained RemissionOpioid Use Disorder, Severe, in Early RemissionMajor Depressive Disorder
Withdrawn·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use

Johns Hopkins University

Opioid Use Disorder
Recruiting·Phase 2·ketamine

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

Wake Forest University Health Sciences

Pain ManagementOpioid UseProstate Cancer
Terminated·Phase 1·ketamine

Acute Pain Management in Patients on Opioid Replacement Therapy

University of California, San Francisco

Opioid-use DisorderPain, Acute
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Wellcome Leap Psilocybin for OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·N/A·ketamine

Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee Arthroplasty

State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia

Knee ArthroplastyPostoperative PainPain Management+3 more
Completed·N/A·ketamine

The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery

Tiva Group

Pharmacological ActionPost Operative PainOpioid Use+2 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin After Trauma Surgery for Pain

Trent Emerick

Pain ManagementPostoperative Pain

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.