24 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 100 of 133 trials
Completed·Phase 1·ketamine
Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery
Assiut University
Acute PainChronic Pain
Suspended·Phase 4·ketamine
Intraoperative Ketamine on Chronic Pain After Mastectomy
The University of Hong Kong
Chronic Pain
Recruiting·Phase 2·psilocybin
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Chronic Neuropathic PainPain Management
Completed·N/A·ketamine
Use of Ketamine in Severe Pain Syndromes
Erasme University Hospital
Pain, IntractablePain, ChronicPain Syndrome+1 more
Completed·Phase 4·ketamine
Superficial Cervical Plexus Block Versus Ketamine in the Prevention of Chronic Pain After Thyroidectomy
University Tunis El Manar
Chronic PainThyroidectomy
Unknown·N/A·psilocybin
Psilocybin in Patients With Fibromyalgia: EEG-measured Brain Biomarkers of Action
Imperial College London
Fibromyalgia
Completed·Phase 4·ketamine
Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy
University Tunis El Manar
Postoperative Pain
Unknown·N/A·ketamine
Ketamine in Robot-assisted Thyroidectomy
Seoul National University Hospital
ThyroidAcute PainChronic Pain
Completed·Phase 4·ketamine
The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients
Rigshospitalet, Denmark
Postoperative PainChronic PainAnalgesics
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Recruiting·Phase 4·ketamine
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
Neuropathic PainPTSD
Completed·Phase 3·ketamine
Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Alliance for Clinical Trials in Oncology
Chronic Myeloproliferative DisordersLeukemiaLymphoma+7 more
Recruiting·Phase 4·ketamine
Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes
Peking University First Hospital
Scoliosis CorrectionPostoperative AnalgesiaEsketamine+2 more
Completed·Phase 3·ketamine
Ketamine Infusion for Comorbid PTSD and Chronic Pain
VA Ann Arbor Healthcare System
PTSDChronic Pain
Completed·Phase 4·ketamine
Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
Mahidol University
Pain, AcutePain, ChronicPain, Neuropathic
Completed·Phase 4·ketamine
Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients
Brigham and Women's Hospital
Postoperative Pain
Active, Not Recruiting·N/A·ketamine
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Wilderman Medical Clinic
Fibromyalgia
Unknown·Phase 4·ketamine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
AXIS Spine Center- a division of Northwest Specialty Hospital
Revision Spine SurgeryFusion of SpineCervical Fusion+1 more
Unknown·N/A·ketamine
Opioid-free Anesthesia in Thyroidectomies
Aretaieion University Hospital
Pain, Post OperativePain, AcutePain, Chronic+9 more
Unknown·N/A·ketamine
Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome.
Centre Hospitalier Universitaire de Charleroi
Fibromyalgia
Terminated·Phase 2·ketamine
Ketamine in Chronic Kid's (KiCK) Pain
Medical University of South Carolina
Chronic Pain
Completed·Phase 4·ketamine
Preventing Pain After Heart Surgery
Barts & The London NHS Trust
PainHyperalgesiaChronic Illness+1 more
Completed·Phase 4·ketamine
Psychotherapy for Ketamine's Enhanced Durability in Chronic Neuropathic Pain: A Randomized Controlled Pilot Trial
Unity Health Toronto
Neuropathic Pain
Completed·N/A·ketamine
Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC
Centre Leon Berard
CancerChronic PainNeuropathic Pain+1 more
Completed·Phase 2·ketamine
The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
University Hospital, Lille
Pain, Postoperative
Recruiting·Phase 2·psilocybin
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Treatment Resistant DepressionChronic Pain
Completed·Phase 4·ketamine
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
Imperial College Healthcare NHS Trust
Chronic Postoperative Pain
Terminated·Phase 1·ketamine
Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
Milton S. Hershey Medical Center
Chronic Pain
Completed·Phase 4·ketamine
Adding Ketamine to Levobupivacaine in Paravertebral Block in Thoracotomy
Tanta University
KetamineLevobupivacaineParavertebral Block+2 more
Recruiting·Phase 1·ketamine
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
Rush University Medical Center
Pain, Neuropathic
Completed·Phase 4·ketamine
Dexmedetomidine-Ketamine Infusion in Breast Surgeries
Tanta University
Total Intravenous Anesthesia
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Completed·N/A·ketamine
Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain
Seoul National University Hospital
Chronic Post-thoracotomy Pain
Recruiting·N/A·ketamine
Ketamine Treatment Plans for Chronic Conditions
RIVER Foundation
Chronic PainDepressive DisorderAnxiety Disorders+1 more
Terminated·N/A·Other
Prevention of Phantom Limb Pain After Transtibial Amputation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phantom Limb PainChronic PainPrevention
Unknown·Phase 3·ketamine
Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting
University of Washington
Chronic Pain
Recruiting·N/A·ketamine
Ketamine Enhances Analgesia and Mood in Chronic Pain Patients
Salem Anaesthesia Pain Clinic
Mood Disorder; OpioidMood Insomnia
Completed·N/A·ketamine
Plasma Concentration of Ketamine and Norketamine .
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Pain
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Completed·N/A·ketamine
Infusion Treatments of Chronic Peripheral Neuropathic Pain
Hacettepe University
Neuropathic Pain
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
Oregon Health and Science University
Chronic Pelvic Pain
Completed·Phase 1·psilocybin
Psilocybin Combined With Multidisciplinary Palliative Care in Demoralized Cancer Survivors With Chronic Pain
Emory University
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
Terminated·N/A·Other
Anesthesia and Functional Connectivity: An Analysis of fMRI Changes
University of Michigan
Changes in Brain Network Connectivity
Recruiting·Phase 2·psilocybin
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
Opioid DependenceChronic Pain
Completed·N/A·ketamine
Simultaneous Application of Ketamine and Lidocaine During an Ambulatory Infusion Therapy as a Treatment Option in Refractory Chronic Pain Conditions
University Hospital, Basel, Switzerland
Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Terminated·Phase 2·ketamine
Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery
Jacques E. Chelly
Opioid DependenceChronic Pain
Completed·Phase 4·ketamine
Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain
Allevio Pain Management Clinic
Chronic Neuropathic Pain and Fibromyalgia
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Early Phase 1·ketamine
The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.
National and Kapodistrian University of Athens
Opioid-Refractory Chronic Cancer-Related Pain
Completed·N/A·Other
Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Christophe Aveline, MD
Postoperative PainNeuropathic Pain
Unknown·Early Phase 1·ketamine
Prevention of Post Mastectomy With Intraoperative Ketamine
Brigham and Women's Hospital
Pain, PostoperativePost-Mastectomy Chronic Pain Syndrome
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Recruiting·Phase 1·psilocybin
Psilocybin Therapy for Chronic Low Back Pain
Joshua Woolley, MD, PhD
Chronic Low-back Pain
Unknown·Phase 2·ketamine
Esketamine Combined With Pregabalin on CPSP in Spinal Patients.
Beijing Tiantan Hospital
EsketaminePregabalineChronic Post Operative Pain
Not Yet Recruiting·N/A·Other
Complex Regional Pain Syndrome: Analgesic Outcome
Ciusss de L'Est de l'Île de Montréal
Chronic PainComplex Regional Pain Syndrome
Active, Not Recruiting·Phase 1·ketamine
Effects of Esketamine Versus Magnesium Sulfate on Emotional State and Postoperative Pain in Patients Undergoing Nasal Endoscopic Surgery
The Second People's Hospital of Huai'an
Chronic RhinosinusitisEnhanced Recovery After Surgery
Recruiting·N/A·Other
The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)
4th Military Clinical Hospital with Polyclinic, Poland
Kidney Failure, AcuteMyopathy; DrugsHeart Arrhythmia+4 more
Not Yet Recruiting·N/A·ketamine
Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord Injury
Beijing Tiantan Hospital
Chronic Pain
Recruiting·Phase 4·Other
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
University of Crete
Systemic Inflammatory Response SyndromePostoperative Pain, AcutePostoperative Pain, Chronic+4 more
Terminated·Phase 1·ketamine
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
NYU Langone Health
EndometriosisPost Operative Pain
Unknown·Phase 3·ketamine
Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway
Redar
NeuralgiaChronic PainInflammation
Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
Post Traumatic Stress Disorder
Recruiting·Early Phase 1·psilocybin
Psilocybin-facilitated Treatment for Chronic Pain
University of Alabama at Birmingham
Fibromyalgia, Primary
Recruiting·N/A·Other
Different Treatments in Chronic Pain Patients.
University Ghent
Chronic PainNociplastic Pain
Completed·Phase 3·ketamine
Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Chronic Pain
Unknown·N/A·ketamine
OBSERVATIONAL STUDY OF THE MANAGEMENT OF PATIENTS WITH CHRONIC PAIN
University Hospital, Clermont-Ferrand
Chronic Pain
Completed·Phase 4·ketamine
Effect of Ketamine on Analgesia Post-Cardiac Surgery
Jewish General Hospital
Pain, Postoperative
Completed·Phase 2·ketamine
The Effect of Esketamine Combined With Pregabalin on Chronic Postsurgical Pain in Patients After Craniotomy.
Beijing Tiantan Hospital
Chronic Postsurgical Pain
Recruiting·Phase 2·Other
Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial
Unity Health Toronto
Chronic Neuropathic Pain
Unknown·N/A·ketamine
Lidocaine and Magnesium and Ketamine in Gynecological Surgery
Aretaieion University Hospital
Pain, PostoperativePain, AcutePain, Chronic+8 more
Completed·Phase 2·ketamine
Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain
Hospital de Clinicas de Porto Alegre
Acute PainChronic Pain, WidespreadSchizophrenia
Withdrawn·Phase 2·ketamine
Ketamine and Midazolam Infusions for CRPS: Feasibility Study
Stanford University
Complex Regional Pain Syndromes
Not Yet Recruiting·Early Phase 1·Other
Transition From Acute to Chronic Opioid Use and Chronic Pain
Jacques E. Chelly
Opioid Use Disorder
Unknown·Phase 3·Other
Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery
Ben Lim
Chronic PainAnesthesia
Completed·N/A·ketamine
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Dartmouth-Hitchcock Medical Center
Chronic Low Back Pain
Recruiting·N/A·psilocybin
The Impact of Psilocybin on Pain in Fibromyalgia Patients
Maastricht University
Fibromyalgia
Terminated·N/A·ketamine
Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain
The Cleveland Clinic
PainNausea
Completed·Phase 1·psilocybin
Psilocybin-assisted Therapy for Phantom Limb Pain
University of California, San Diego
Phantom Limb Pain
Completed·Phase 2·ketamine
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
Grace Lim, MD, MS
Obstetric PainPostpartum DepressionBreastfeeding+5 more
Active, Not Recruiting·Phase 4·ketamine
Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression
Stanford University
Chronic PainDepression
Withdrawn·Phase 3·ketamine
Ketamine Sickle Cell Disease
University of South Florida
SC DiseasePain, Chronic
Recruiting·Phase 1·psilocybin
Psilocybin in Chronic Low Back Pain and Depression
Johns Hopkins University
Chronic Low-back PainDepression
Unknown·N/A·DMT
Mindfulness-based Dance/Movement Therapy for Chronic Low Back Pain
Drexel University
Chronic Low-back Pain
Completed·Phase 2·ketamine
The Effect of Perioperative Ketamine on Acute and Chronic Pain After Major Back Surgery
University Hospital, Geneva
Postoperative Pain
Unknown·N/A·ketamine
Electroencephalographic (EEG) Profils for Patients on Intravenous Ketamine.
Assistance Publique - Hôpitaux de Paris
Neuropathic Pain
Withdrawn·Phase 2·ketamine
Compare the Efficacy and Safety of Intranasal Esketamine in Chronic Opioid Refractory Pain
University Hospital, Basel, Switzerland
Cancer Pain
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Unknown·Phase 3·ketamine
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
University of Glasgow
Cancer
Unknown·N/A·Other
Enhanced vs.Standard Pain Management of Patients at Risk for Chronic Post-surgical Pain
University Hospital, Geneva
Chronic Post Surgical Pain
Completed·Phase 2·ketamine
Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding
Assiut University
Breast Cancer
Active, Not Recruiting·Phase 3·ketamine
Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain
NYU Langone Health
Chronic Postsurgical Pain
Recruiting·Phase 3·ketamine
Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches
University Health Network, Toronto
Chronic Daily Headache
Completed·N/A·ketamine
Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine.
Dr. Horst Schmidt Klinik GmbH
Acute PainChronic PainNeuropathic Pain
Unknown·N/A·ketamine
Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder
Peking University
Chronic Visceral PainMajor Depressive Disorder
Completed·N/A·Other
Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart Surgery
Ondokuz Mayıs University
Chronic PainCardiac SurgeryPost Operative Pain
Completed·Phase 2·ketamine
Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?
Helse Møre og Romsdal HF
Rotator Cuff TendinitisChronic Pain
Unknown·Phase 4·Other
Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
Hospices Civils de Lyon
PainBreast Cancer
Recruiting·Phase 1·ketamine
Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
Natalie Lockney
Head and Neck CancerLocally Advanced Head and Neck Carcinoma
More trials available. Refine your search to see specific results.
How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.