Phase 1/2 Trials
5-MeO-DMT Therapy
5-MeO-DMT is distinct from DMT and is being researched for treatment-resistant depression. Found naturally in the Sonoran Desert toad, synthetic versions are now used in clinical trials.
16Clinical Trials
2Companies
0Legal States
FDA StatusPhase 1/2 Trials
Legal PathwayFDA approval pathway (federal)
Also Known As5-methoxy-DMT, toad venom, Bufo alvarius
Clinical Trials
2 trials currently recruiting
Phase 19
Phase 24
Phase 30
Terminated·Phase 2·DMT
Phase 2 Clinical Trial of GH001 in Postpartum Depression
GH Research Ireland Limited
Postpartum DepressionPostnatal Depression
Unknown·N/A·Other
Personality and Drug Use
Psychedelic Data Society
No Conditions Study Focus on Substance Use and Personality
Withdrawn·Phase 2·ibogaine
Trifecta Research Study
Johns Hopkins University
PTSD - Post Traumatic Stress DisorderCognitive DysfunctionBrain Trauma+1 more
Completed·Phase 1·DMT
Safety and Pharmacokinetics of GH002 in Healthy Volunteers
GH Research Ireland Limited
Healthy Volunteers
Completed·Phase 1·DMT
Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI
Biomind Labs Inc.
Mild Cognitive ImpairmentAnxiety StateDepression Anxiety Disorder
Recruiting·N/A·psilocybin
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Companies & Research
Organizations developing 5-MeO-DMT-based therapies