23 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 148 of 96 trials
Active, Not Recruiting·Early Phase 1·MDMA

MDMA-Assisted Therapy for Pathological Narcissism

University of Washington

Narcissism
Completed·Phase 1·MDMA

Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster Dose

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 3·MDMA

MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSD

Dr. Leslie Morland

PTSDRelational Problems
Completed·Phase 1·MDMA

Group MDMA-therapy for Veterans With PTSD

Portland VA Research Foundation, Inc

PTSD
Completed·Early Phase 1·MDMA

Prosocial Effects of MDMA

University of Chicago

MDMA ('Ecstasy')Social Interaction
Completed·Phase 1·MDMA

Acute Effects of R- and S-MDMA in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·MDMA

Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD

Albany Research Institute, Inc.

Post Traumatic Stress Disorder
Completed·Phase 1·MDMA

Food Effects on Bioavailability of MDMA in Healthy Volunteers

Lykos Therapeutics

Pharmacokinetics
Completed·Early Phase 1·MDMA

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

University of Chicago

Stimulant UseMDMA ('Ecstasy')Social Behavior+1 more
Completed·Phase 2·MDMA

Social Anxiety MDMA-Assisted Therapy Investigation

Jason B Luoma

Social Anxiety Disorder
Completed·Phase 1·MDMA

Effects of MDMA-like Substances in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·MDMA

Stanford Regulating Circuits of the Brain Study - MDMA

Stanford University

Healthy
Completed·Phase 2·MDMA

A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)

Remedy

Post Traumatic Stress Disorder
Completed·Early Phase 1·MDMA

Drug Effects on Interpersonal Interaction

University of Chicago

Interaction, Social
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD

VA Loma Linda Health Care System

Post Traumatic Stress DisorderCombat Stress Disorders
Completed·Phase 3·MDMA

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD

Lykos Therapeutics

PTSD
Completed·N/A·MDMA

Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD

Lykos Therapeutics

PTSD
Completed·N/A·MDMA

Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls

University Hospital, Basel, Switzerland

Diabetes Insipidus
Completed·Phase 1·MDMA

Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 3·MDMA

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

MAPS Europe B.V.

PTSD
Completed·Early Phase 1·MDMA

Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction

University Hospital, Basel, Switzerland

Healthy
Completed·Early Phase 1·MDMA

Effects of Drugs on Responses to Brain and Emotional Processes

University of Chicago

Autism Spectrum DisorderHealthy
Completed·Phase 3·MDMA

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Lykos Therapeutics

PTSD
Completed·Phase 1·MDMA

Evaluation of MDMA on Startle Response

Lykos Therapeutics

Startle Response
Completed·Early Phase 1·MDMA

Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·MDMA

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

Lykos Therapeutics

Anxiety
Completed·N/A·MDMA

Effects of MDMA on Emotional and Social Memories

University of Chicago

Healthy
Completed·Phase 2·MDMA

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

Lykos Therapeutics

Social Anxiety in Autistic Adults
Completed·N/A·MDMA

Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Early Phase 1·MDMA

Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

University Hospital, Basel, Switzerland

HealthySubstance-related DisorderMood Disorder
Completed·Phase 2·MDMA

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 1·MDMA

Influence of Bupropion on the Effects of MDMA

University Hospital, Basel, Switzerland

HealthySubstance-related Disorders
Completed·Early Phase 1·MDMA

Effects of MDMA and Methylphenidate on Social Cognition

University Hospital, Basel, Switzerland

Social Cognition
Completed·Phase 1·MDMA

Emotional Effects of Methylphenidate and MDMA in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·MDMA

Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·Phase 1·MDMA

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers

Lykos Therapeutics

Psychological Effects of Study Drug
Completed·N/A·MDMA

Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·Phase 2·MDMA

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·N/A·MDMA

Naturalistic Study Into the Hangover Effects of MDMA

Utrecht Institute for Pharmaceutical Sciences

Hangover
Completed·Phase 2·MDMA

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·N/A·MDMA

Effects of MDMA on Social and Emotional Processing

University of Chicago

Drug Addiction
Completed·Phase 1·MDMA

Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Completed·N/A·MDMA

Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.

California Pacific Medical Center Research Institute

MDMA Discontinuation Syndrome
Completed·Phase 1·MDMA

Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.