Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers

Inclusion Criteria:

* Engaged in a sponsor-supported program for training therapists to perform MDMA-assisted psychotherapy research
* Are at least 21 years old
* Are willing to follow all rules and restrictions related to study participation, including restrictions on medication use for a week prior to experimental sessions and restrictions on food and alcohol consumption on the day prior to each experimental session
* Are willing to remain overnight at the study site
* Agree to have transportation other than driving themselves after the integrative session on the day after each experimental session
* Are willing to be contacted via telephone for all necessary telephone contacts
* If a woman of childbearing potential, must have a negative pregnancy test and agree to use an effective form of birth control
* Are proficient in speaking and reading English
* Agree to have all clinic visit sessions recorded to audio and video

Exclusion Criteria:

* Are pregnant or nursing, or are women of child bearing potential who are not practicing an effective means of birth control
* Weigh less than 48 kg
* Have used "ecstasy" (material represented as containing MDMA) within 6 months of the MDMA session
* Require ongoing therapy with a psychotropic drug
* Meet DSM-V criteria for substance abuse or dependence for any substance
* Unable to give adequate informed consent
* Upon review of past and current drugs/medication must not be on or have taken a medication that is exclusionary
* Upon review of medical or psychiatric history must not have any current or past diagnosis that would be considered a risk to participation in the study