421 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145192 of 421 trials
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Alcohol Use Disorder

University of Sydney

Alcohol Use DisorderAlcohol DependenceDepression+1 more
Not Yet Recruiting·N/A·Other

Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients

Beijing Friendship Hospital

Opioid-Free AnesthesiaPOCDRecovery Quality+1 more
Not Yet Recruiting·Phase 4·ketamine

Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery

National Taiwan University Hospital

Head and Neck CancerAnesthesiaRenal Protection+2 more
Not Yet Recruiting·Phase 2·ketamine

Quelling of Excitotoxicity in Acute Stroke With Ketamine

Lower Merion Neurology Research Foundation

Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·LSD

LSD Treatment for Persons With Alcohol Use Disorder

Felix Mueller

Alcohol Use Disorder (AUD)
Not Yet Recruiting·N/A·Other

Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease

Fondation Hôpital Saint-Joseph

Procedural PainCongenital Heart DiseaseHeart Surgery+1 more
Not Yet Recruiting·Phase 4·Other

Anesthesia and Non-small Cell Lung Cancer Recurrence

Samsung Medical Center

Non-small Cell Lung CancerSurgeryAnesthesia
Not Yet Recruiting·Phase 2·ketamine

Ketamine Treatment for PTSD and MDD in TBI

Minneapolis Veterans Affairs Medical Center

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Early Phase 1·ketamine

Ketamine in Severe Traumatic Brain Injury

University of Texas Southwestern Medical Center

Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Early Phase 1·ketamine

Ketamine and Propofol NeuroImaging

Keith M Vogt

AnesthesiaPain
Recruiting·Phase 2·psilocybin

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Region Skane

Anorexia Nervosa
Recruiting·Phase 2·psilocybin

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

University of Washington

AnxietyDepressionHematopoietic and Lymphatic System Neoplasm+1 more
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Alan Davis

Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 1·psilocybin

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

Gustavo Vazquez

DemoralizationSafety
Recruiting·Early Phase 1·MDMA

MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital

Fibromyalgia
Recruiting·Phase 2·ketamine

A Clinical Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression

Daniel Lindqvist

Major Depressive Disorder (MDD)
Recruiting·Phase 2·ketamine

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Mohsen Saidinejad

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·Phase 1·DMT

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

University Hospital, Basel, Switzerland

5-methoxy-dimethyltryptamine (5-MeO-DMT)
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Phase 2·ketamine

Ketamine for Veterans With Parkinson's Disease

VA Office of Research and Development

Parkinson's Disease
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·N/A·Other

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

Zeliha Alicikus

Critically IllIntubation ComplicationOxygenation+3 more
Recruiting·Phase 1·MDMA

MDMA-Assisted Therapy for Mental Healthcare Providers

Rachel Yehuda

Mental Wellbeing
Recruiting·Phase 1·psilocybin

Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD

Suzanne "Sue" Sisley MD

PTSD
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin

Safety Profile of Psilocybin for Cocaine Use Disorder

University of California, Los Angeles

Cocaine Use Disorder
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·Phase 2·Other

Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial

Unity Health Toronto

Chronic Neuropathic Pain
Recruiting·Phase 1·ketamine

Pilot Study of RR-HNK in OCD

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

The Ketamine Research Foundation

Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Recruiting·Phase 1·psilocybin

RCT of Psilocybin-assisted CBT for Depression

University of California, Los Angeles

Major Depressive Diorder
Recruiting·Phase 3·psilocybin

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Bruyère Health Research Institute.

Psychological Distress
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Recruiting·Phase 3·psilocybin

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
Recruiting·Phase 2·ketamine

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

VA Office of Research and Development

Chronic Low Back PainDepression
Recruiting·Phase 2·MDMA

A Phase 2A Trial of MM402 for Autism Spectrum Disorder

Definium Therapeutics US, Inc.

Autism Spectrum DisorderASD
Recruiting·Phase 2·ketamine

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

ACADIA Pharmaceuticals Inc.

Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Recruiting·Phase 1·psilocybin

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

Medical University of Vienna

Depression - Major Depressive DisorderAnhedonia
Recruiting·Phase 1·psilocybin

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

University of California, Berkeley

Aging
Recruiting·Phase 2·psilocybin

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

University of British Columbia

Opioid DependenceChronic Pain
Recruiting·Phase 2·psilocybin

Wellcome Leap Psilocybin for OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.