421 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 97–144 of 421 trials
Not Yet Recruiting·Phase 4·ketamine
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
Ain Shams University
Upper Gastrointestinal EndoscopyAnesthesia
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Post Traumatic Stress DisorderPTSD
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·Phase 4·ketamine
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
Assiut University
Varicocelectomy
Not Yet Recruiting·N/A·Other
Complex Regional Pain Syndrome: Analgesic Outcome
Ciusss de L'Est de l'Île de Montréal
Chronic PainComplex Regional Pain Syndrome
Not Yet Recruiting·Phase 2·Other
Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002
Global Coalition for Adaptive Research
Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 4·ketamine
Ketamine for the Treatment of Refractory Status Epilepticus
Thomas Jefferson University
Refractory Status Epilepticus
Not Yet Recruiting·N/A·ketamine
Ketodex Versus Opioid Based Anesthesia in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.
Cairo University
Morbid Obesity
Not Yet Recruiting·N/A·Other
Intravenous Sedation and Analgesia Versus Local Anesthesia During Microwave Ablation of Benign Thyroid Nodules
Suez University
Benign Thyroid Nodule
Not Yet Recruiting·Phase 2·psilocybin
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Not Yet Recruiting·N/A·LSD
Microdosing LSD in Women With Premenstrual Disorders
Friederike Holze
PMSPMDD
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·Phase 3·ketamine
Ketamine Sedation in the ICU (KANINE) RCT
McMaster University
Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 3·ketamine
Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Depressive Disorder
Not Yet Recruiting·Phase 4·ketamine
The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression
The First Hospital of Jilin University
DepressedBariatric Surgery
Not Yet Recruiting·Phase 1·psilocybin
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Manoj Doss
Healthy
Not Yet Recruiting·Phase 3·Other
A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
University Hospital, Montpellier
Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
Not Yet Recruiting·Phase 4·Other
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
Siirt Training and Research Hospital
ObesityBariatric Surgery
Not Yet Recruiting·N/A·ketamine
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
IVO JURISIC
Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·Phase 3·Other
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
Asklepion Pharmaceuticals, LLC
Sickle Cell Disease
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Anqing Municipal Hospital
EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Caregiver Distress
Not Yet Recruiting·N/A·Other
Effectiveness of the Combination Strategy of Disease-Modifying Therapy and the Yishen Daluo Yin Modified Formula for Multiple Sclerosis
Ying Gao
RRMS
Not Yet Recruiting·Phase 4·ketamine
Ketamine for Postherpetic Neuralgia With Depression
Huazhong University of Science and Technology
Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine
Ketamine and Lidocaine Infusion in Refractory Chronic Migraine
Assiut University
Refractory Chronic Migraine
Not Yet Recruiting·N/A·Other
B-cell Depletion in Offspring to Women With MS Under Immunomodulatory Treatment
Region Stockholm
Multiple SclerosisB-Cell DeficiencyOffspring, Adult+2 more
Not Yet Recruiting·N/A·Other
Cladribine Tablets as an Exit Therapy Strategy
University Hospital, Strasbourg, France
Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Not Yet Recruiting·Phase 3·ketamine
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Federal University of São Paulo
Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
University of Zurich
Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
COPD (Chronic Obstructive Pulmonary Disease)ALS (Amyotrophic Lateral Sclerosis)MS (Multiple Sclerosis)+2 more
Not Yet Recruiting·N/A·Other
Opioid-free Anesthesia and Quality of Recovery After General Anesthesia
Selcuk University
Opioid-free AnesthesiaGeriatric Population
Not Yet Recruiting·Phase 4·ketamine
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
bo xu
General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·Phase 4·Other
Comparative Study of Opioid-Free Anesthesia Versus Opioid Anesthesia in Patients Undergoing Laparoscopic Cholecystectomy
Assiut University
Laparoscopic Cholecystectomy
Not Yet Recruiting·Phase 1·ketamine
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
Massachusetts General Hospital
DepressionSuicide
Not Yet Recruiting·Phase 1·ketamine
Ketamine for Combined Depression and Alcohol Use Disorder
University Hospital of North Norway
DepressionAlcohol Use Disorder
Not Yet Recruiting·Phase 2·Other
PEX010-Assisted Therapy for Stimulant Use Disorder: A Safety, Feasibility and Efficacy Study
Filament Health Corp.
Stimulant Use Disorder
Not Yet Recruiting·Phase 3·DMT
Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)
University Hospital, Strasbourg, France
Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·N/A·Other
Acupressure's Impact on Pain and Physiological Parameters in Infants Undergoing Cardiac Catheterization
Baskent University
Cardiac Catheterization
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 4·ketamine
Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia
Assiut University
Post Cesarean Analgesia
Not Yet Recruiting·N/A·ketamine
Opioid Free Anesthesia Versus Opioid Based Anesthesia
Ain Shams University
Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·N/A·psilocybin
The Effects of Psilocybin on Shared Experience in Film Processing
Western University, Canada
Disorders of ConsciousnessPsychedelic Experiences
Not Yet Recruiting·Phase 1·Other
Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma
Assistance Publique Hopitaux De Marseille
MedulloblastomaEpendymoma
Not Yet Recruiting·Phase 3·Other
Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context
Dr George Medvedev
MigraineChronic Migraine
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.