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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 4996 of 96 trials
Completed·Phase 1·MDMA

Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-related DisordersAmphetamine-related Disorders
Completed·N/A·MDMA

Role of Serotonin in Acute and Subacute MDMA Effects

California Pacific Medical Center Research Institute

MDMA Mechanism of Action
Completed·N/A·MDMA

Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine]

California Pacific Medical Center Research Institute

Healthy
Completed·Phase 2·MDMA

Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·N/A·MDMA

Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging

University of Zurich

Amphetamine-Related DisordersAmphetamine Abuse
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 1·MDMA

Neurobiology and Pharmacokinets of Acute MDMA Administration

National Institute on Drug Abuse (NIDA)

Substance-Related Disorders
Completed·Phase 1·MDMA

-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms

Parc de Salut Mar

MetabolismInteraction
Completed·N/A·MDMA

The NeXT Study; The Netherlands XTC Toxicity Study

UMC Utrecht

Ecstasy (Drug)N-Methyl-3,4-MethylenedioxymethamphetaminePsychopathology
Completed·Phase 1·MDMA

Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)

University Hospital, Basel, Switzerland

Mood DisorderSubstance-Related DisordersAmphetamine-Related Disorders
Enrolling by Invitation·Phase 2·MDMA

High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD

ARQ National Psychotrauma Centre

Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·Phase 2·MDMA

MDMA Plus Exposure Therapy for PTSD

Emory University

PTSD
No Longer Available·N/A·MDMA

A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD

Lykos Therapeutics

Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers

Nautilus Sanctuary

Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·Phase 1·MDMA

MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

Lykos Therapeutics

PharmacokineticsHepatic Impairment
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Recruiting·Early Phase 1·MDMA

MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital

Fibromyalgia
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·Phase 1·MDMA

MDMA-Assisted Therapy for Mental Healthcare Providers

Rachel Yehuda

Mental Wellbeing
Recruiting·Phase 2·MDMA

A Phase 2A Trial of DT402 for Autism Spectrum Disorder

Definium Therapeutics US, Inc.

Autism Spectrum DisorderASD
Recruiting·Phase 2·MDMA

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·MDMA

MDMA in Borderline Personality Disorder

Yale University

Borderline Personality Disorder
Recruiting·Phase 1·MDMA

Comparative Acute Effects of R-MDMA and S-MDMA in Healthy Participants

University Hospital, Basel, Switzerland

Healthy
Recruiting·Phase 2·MDMA

Dose Optimization of MDMA-Assisted Therapy for PTSD

Bronx VA Medical Center

Posttraumatic Stress Disorder
Recruiting·Phase 1·MDMA

Tolerability of MDMA in Schizophrenia

Anya Bershad, MD, PhD

Schizophrenia
Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Stephen Robert Marder

Post Traumatic Stress Disorder
Recruiting·Phase 2·MDMA

MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder

Patricia Suppes

PTSD
Recruiting·N/A·MDMA

Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls

University Hospital, Basel, Switzerland

Central Diabetes Insipidus
Recruiting·Phase 2·MDMA

MDMA-Assisted CBCT for PTSD vs CBCT RCT

Remedy

Post Traumatic Stress Disorder
Recruiting·Phase 3·MDMA

MDMA-assisted Massed Prolonged Exposure for PTSD

Healing Breakthrough

Post-Traumatic Stress Disorder
Recruiting·Phase 2·MDMA

MDMA for Co-occurring PTSD and OUD After Childbirth

University of New Mexico

Stress Disorders, Post-TraumaticOpioid Use Disorder
Recruiting·Phase 2·MDMA

MDMA for AUD/PTSD Comorbidity

Carolina L Haass-Koffler

Alcohol Use DisorderPost Traumatic Stress Disorder
Recruiting·Phase 2·MDMA

MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other

Sunstone Medical

CancerAdjustment Disorders
Terminated·Phase 2·MDMA

Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD

Lykos Therapeutics

PTSD
Terminated·Phase 2·MDMA

Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Terminated·Phase 2·MDMA

MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer

Brigham and Women's Hospital

Anxiety DisorderCancer
Unknown·Phase 2·MDMA

Preliminary Effectiveness of Individual and Group MDMA-assisted Therapy for Israeli Veterans With PTSD and Moral Injury.

HaEmek Medical Center, Israel

Post Traumatic Stress DisorderMoral InjuryMDMA ('Ecstasy')
Unknown·N/A·MDMA

Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy

Apollo Neuroscience, Inc.

Stress Disorders, Post-Traumatic
Unknown·Phase 1·MDMA

Abuse Potential and Human Pharmacology of Methylone

Germans Trias i Pujol Hospital

Substance UseHealthy Subjects
Unknown·Phase 3·MDMA

Epigenetics and MDMA-Assisted Psychotherapy for PTSD

University of Southern California

PTSD
Unknown·Phase 1·MDMA

Bristol Imperial MDMA in Alcoholism Study

Imperial College London

Alcohol Use Disorder
Withdrawn·Phase 2·MDMA

A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders

Lykos Therapeutics

Anorexia Nervosa Restricting TypeBinge-Eating Disorder
Withdrawn·Phase 2·MDMA

MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents

University of California, Los Angeles

PTSD, Post Traumatic Stress DisorderAdolescentsPsychotherapy
Withdrawn·Phase 1·MDMA

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Lykos Therapeutics

Psychological Effects of Study Drug
Withdrawn·Phase 1·MDMA

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

Yale University

Post Traumatic Stress Disorder
Withdrawn·Phase 2·MDMA

Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans

Lykos Therapeutics

PTSD
Withdrawn·Phase 2·MDMA

Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.