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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 673720 of 1013 trials
Recruiting·N/A·ketamine

Glutamate Emotion Memory Study

University of Oxford

Treatment Resistant DepressionDepressionMajor Depressive Disorder
Recruiting·Phase 3·ketamine

Ketamine Treatment of Youth Suicide Attempters

Tatiana Falcone, MD

Suicide, Attempted
Recruiting·Phase 3·ketamine

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

University Health Network, Toronto

Chronic Daily Headache
Recruiting·Phase 1·ketamine

The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects

Medical University of Vienna

Major Depressive Disorder
Recruiting·Phase 4·ketamine

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Loyola University

Pain, ProceduralMinor LacerationAbscess
Recruiting·Phase 2·ketamine

Ketamine to Treat Patients With Post-comatose Disorders of Consciousness

University of Liege

Disorder of Consciousness
Recruiting·Phase 1·ketamine

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Natalie Lockney

Head and Neck CancerLocally Advanced Head and Neck Carcinoma
Recruiting·N/A·ketamine

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

University of Milano Bicocca

Status EpilepticusCardiac Arrest
Recruiting·Phase 4·ketamine

Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)

University Hospital, Clermont-Ferrand

Refractory Chronic Cluster Headache
Recruiting·Phase 4·ketamine

Ketamine in Acute Brain Injury Patients.

Geert Meyfroidt, MD, PhD

Brain Injuries, Traumatic
Recruiting·N/A·ketamine

Long-term Observation of Participants With Mood Disorders

National Institute of Mental Health (NIMH)

DepressionSuicide Risk
Recruiting·Phase 1·ketamine

Understanding Ketamine's Dissociative Effects (KD Study)

Stanford University

Epilepsy
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Opioid Use Disorder

University of Utah

Opioid-use Disorder
Recruiting·Phase 2·ketamine

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Sam Tyagi

Descending Aortic DissectionPostoperative PainThoracoabdominal Aortic Aneurysm
Recruiting·N/A·ketamine

University of Iowa Interventional Psychiatry Service Patient Registry

Mark Niciu

Treatment Resistant DepressionMajor Depressive EpisodeMajor Depression+4 more
Recruiting·Phase 4·ketamine

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

University of Oklahoma

Hemorrhoids
Recruiting·Phase 2·ketamine

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation

Naveen Poonai

FractureDislocation
Recruiting·Phase 1·ketamine

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

National Institute of Mental Health (NIMH)

DepressionMajor Depressive DisorderMajor Depression
Recruiting·N/A·ketamine

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Göteborg University

ObesityPain, Postoperative
Recruiting·Phase 4·ketamine

Premedication for Less Invasive Surfactant Administration

University of Oulu

Surfactant Deficiency Syndrome Neonatal
Recruiting·N/A·ketamine

Anesthetics and Analgesics in Children

Chi Dang Hornik

AnesthesiaPain
Recruiting·N/A·ketamine

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

Salem Anaesthesia Pain Clinic

Mood Disorder; OpioidMood Insomnia
Recruiting·N/A·ketamine

Dexmedetomidine and Ketamine in VATS Surgery

Ciusss de L'Est de l'Île de Montréal

Postoperative PainOpioid Use
Recruiting·Phase 4·ketamine

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

University of Saskatchewan

Treatment Resistant DepressionKetamine
Recruiting·Phase 1·ketamine

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

National Institute of Mental Health (NIMH)

Healthy VolunteerMajor Depressive DisorderDepression
Recruiting·N/A·ketamine

Imaging SV2A in Mood Disorders

Yale University

Major Depressive DisorderPost-Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Neurobiology of Suicide

National Institute of Mental Health (NIMH)

Healthy VolunteersDepression
Recruiting·Phase 2·ketamine

Ketamine Alcohol (in Treatment-Resistant Depression)

Mark Niciu

Magnetic Resonance ImagingMajor DepressionAlcoholism
Suspended·Early Phase 1·ketamine

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

University of Wisconsin, Madison

Posttraumatic Stress Disorder
Suspended·Phase 4·ketamine

Ketamine for Sedation in Severe Traumatic Brain Injury

Henry M. Jackson Foundation for the Advancement of Military Medicine

Severe Traumatic Brain InjuryIntracranial HypertensionIntracranial Hemorrhage, Hypertensive
Suspended·Phase 1·ketamine

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

Texas A&M University

HealthyMajor Depressive DisorderTreatment Resistant Depression
Suspended·Phase 2·ketamine

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

Wake Forest University Health Sciences

Pain ManagementOpioid UseProstate Cancer
Suspended·N/A·ketamine

Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine Treatment

University of Pittsburgh

Depression
Suspended·Phase 1·ketamine

Glutamatergic Mechanisms: Aim2

New York State Psychiatric Institute

Healthy
Suspended·Phase 2·ketamine

Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia

PharmaTher Inc.

DyskinesiasMovement DisordersCentral Nervous System Diseases+2 more
Suspended·Phase 4·ketamine

IM Ketamine vs Midazolam for Suicidal ER Patients

New York State Psychiatric Institute

Depression, UnipolarDepression, BipolarSuicidal Ideation
Suspended·Phase 1·ketamine

Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1)

New York State Psychiatric Institute

Healthy
Suspended·Phase 3·ketamine

Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion

Dr. Marie Eve Sophie Bussiere-Cote

Abortion in First Trimester
Suspended·Phase 3·ketamine

Ketamine Versus Electroconvulsive Therapy in Depression

University of Ottawa

Depressive Disorder, MajorBipolar Depression
Suspended·Phase 2·ketamine

A Study of Human Multi-Sensory Integration

University of Pennsylvania

Anesthesia Awareness
Suspended·N/A·ketamine

Ketamine vs Propofol for Sedation During Pediatric Bronchoscopy

Rabin Medical Center

Paediatric Flexible Bronchoscopy
Suspended·Phase 3·ketamine

Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient

University Hospital, Clermont-Ferrand

Alcoholic PatientCarcinological Surgery ORL
Terminated·N/A·ketamine

Role Of Non-Specific Effects in The Treatment of Depression With Esketamine

Yale University

Depressive Episode
Terminated·Phase 2·ketamine

Ketamine for OUD and Suicidal Ideation in the ED

Brigham and Women's Hospital

Opioid Use DisorderSuicidal Ideation
Terminated·N/A·ketamine

Behavioural Activation Therapy and Esketamine for Resistant Depression

The Royal's Institute of Mental Health Research

Depressive Disorder, Treatment-ResistantDepressive Disorder, MajorBipolar Disorder
Terminated·Phase 4·ketamine

Ketamine-assisted Therapy for Advanced GI Cancer

Brian Anderson, MD

Pancreatic Ductal AdenocarcinomaPain, AcuteGastrointestinal Cancers+1 more
Terminated·Early Phase 1·ketamine

Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers

University of Utah

Gastrointestinal CancerDepressionAnxiety
Terminated·Phase 1·ketamine

[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine

National Institute of Mental Health (NIMH)

Depression
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.