RecruitingN/Aketamine
Anesthetics and Analgesics in Children
Sponsored by Chi Dang Hornik
NCT ID
NCT03427736
Target Enrollment
460 participants
Start Date
2018-12-13
Est. Completion
2026-09-09
About This Study
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Conditions Studied
Interventions
- •Ketorolac Tromethamine
- •Hydromorphone
- •Ketamine
- •Oxycodone
- •Morphine
Eligibility
Age:0 Years - 17 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: 1. 0 to \<18 years of age at time of enrollment (must see applicable appendix for details as not all appendices enroll across the entire age range) 2. Parent and/or participant (if applicable) is able to understand the consent process and provides informed consent and HIPAA Authorization (if applicable) 3. Participant provides assent as required by the institutional review board (IRB) or research ethics board (REB) 4. Receiving one or more drugs of interest (DOI) per local standard of care 5. Meeting DOI-specific inclusion criteria (See Appendices) Exclusion Criteria: 1. Known pregnancy 2. Extracorporeal life support (i.e., ECMO, dialysis, ventricular assist device) 3. Any condition which would make the participant, in the opinion of the investigator, unsuitable for the study
Study Locations (13)
Lucile Packard Children's Hospital
Stanford, California, United States
Children's Hospital Colorado
Aurora, Colorado, United States
Alfred I. DuPont Hospital for Children
Wilmington, Delaware, United States
Ann and Robert H. Lurie Childrens Hospital of Chicago
Chicago, Illinois, United States
Cardinal Glennon Children's Hospital
St Louis, Missouri, United States
Washington University School of Medicine
St Louis, Missouri, United States
Duke University Medical Center
Durham, North Carolina, United States
Oregon Health and Science University
Portland, Oregon, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Dell Children's Medical Center of Texas
Austin, Texas, United States
+3 more locations