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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 625672 of 1695 trials
Completed·Phase 4·ketamine

Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department

Carilion Clinic

Acute PainPain
Completed·Phase 4·ketamine

Comparing Ketamine and Propofol Anesthesia for Electroconvulsive Therapy

University of Saskatchewan

Treatment Resistant Depression
Completed·Phase 4·ketamine

Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.

Balikesir University

Arthroscopy
Completed·Phase 1·ketamine

Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults

Takeda

Ketamine-Induced Brain Activity ChangesPsychotic-like Symptoms
Completed·N/A·ketamine

The Effects of the Anesthetic Ketamine in Young Children Undergoing Procedural Sedation

The Hospital for Sick Children

Trauma
Completed·Phase 4·ketamine

Management of Pain in Lumbar Arthrodesis

Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta

Pain, Postoperative
Completed·Phase 4·ketamine

Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial

University Hospital, Basel, Switzerland

Postoperative Delirium
Completed·Phase 2·ketamine

Ketamine Plus Lithium in Treatment-Resistant Depression

Icahn School of Medicine at Mount Sinai

Depression
Completed·Early Phase 1·ketamine

Examining The Effect Of Ketamine On Glutamate/Glutamine Cycling

Yale University

Depression
Completed·N/A·Other

Pediatric Laser Acupuncture and Renal Biopsy

University of California, San Francisco

PainAnxiety
Completed·Phase 4·ketamine

Ketamine and Propofol for Upper Endoscopy

The Hospital for Sick Children

Anesthesia
Completed·Early Phase 1·LSD

Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·MDMA

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·ketamine

Action of Ketamine in Treatment-Resistant Depression

University of Ottawa

Treatment-resistant Depression
Completed·Phase 1·psilocybin

Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

PsilocybinHallucinogensPharmacologic Actions+3 more
Completed·Phase 4·ketamine

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

Albany Medical College

Idiopathic ScoliosisPost-operative Pain
Completed·Early Phase 1·ketamine

Characterizing Clinical and Pharmacological Neuroimaging Biomarkers

Yale University

Cognitive Impairment
Completed·Phase 4·ketamine

ACL Repair and Multimodal Analgesia

University of Wisconsin, Madison

Pain
Completed·Phase 4·ketamine

Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department

Antonios Likourezos

Pain
Completed·Phase 4·ketamine

NMDA Antagonists in Bipolar Depression

New York State Psychiatric Institute

Bipolar Disorder
Completed·N/A·ketamine

The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Aga Khan University

Cholelithiasis
Completed·N/A·ketamine

Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Completed·Phase 1·MDMA

Influence of Bupropion on the Effects of MDMA

University Hospital, Basel, Switzerland

HealthySubstance-related Disorders
Completed·N/A·ketamine

Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation

Inje University

Psychomotor Agitation
Completed·Phase 1·ketamine

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

Biogen

Schizophrenia
Completed·Phase 4·ketamine

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

HealthPartners Institute

Pain
Completed·Phase 1·ketamine

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 2·ketamine

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine

Isfahan University of Medical Sciences

Closed Multiple Fractures of Upper and Lower Limbs
Completed·Phase 2·ketamine

A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion

NYU Langone Health

Spinal Fusion
Completed·Phase 4·Other

Natalizumab Temporary Discontinuation Study

University at Buffalo

Multiple Sclerosis
Completed·Phase 4·ketamine

Intra-nasal Ketamine for Analgesia in the Emergency Department

Lions Gate Hospital

Pain
Completed·Phase 1·ketamine

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

Rhode Island Hospital

Pain
Completed·Phase 2·ketamine

A Study of Ketamine in Patients With Treatment-resistant Depression

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·Early Phase 1·MDMA

Effects of MDMA and Methylphenidate on Social Cognition

University Hospital, Basel, Switzerland

Social Cognition
Completed·Phase 1·ketamine

Changes in Striatal [11C]ORM-13070 Binding Elicited by Changing Levels of Endogenous Noradrenaline

University of Turku

Changes in Striatal [11C]ORM-13070 Binding.
Completed·N/A·ketamine

Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris

University of Washington

Monitoring, Intraoperative
Completed·Phase 2·ketamine

Low Dose Ketamine VR Analgesia During Burn Care Procedure

National Institute of General Medical Sciences (NIGMS)

Burn
Completed·N/A·Other

Analysis of Lymphocyte Cell Surface Adhesion Marker Expression in Natalizumab Population With Active Control

John F. Foley, MD

Multiple Sclerosis
Completed·Phase 2·ketamine

A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·Phase 4·ketamine

Ketamine in the Treatment of Suicidal Depression

New York State Psychiatric Institute

Major Depressive DisorderSuicidal Ideation
Completed·N/A·ketamine

PET Imaging of mGLuR5 With Drug Challenge

Yale University

Major Depressive DisorderPost-Traumatic Stress Disorder (PTSD)
Completed·Phase 4·ketamine

Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions

Baskent University

Conscious Sedation Failure During Procedure
Completed·N/A·ketamine

Treatment of Suicidal Ideation With Intravenous Ketamine Infusion

University of Alabama at Birmingham

DepressionSuicidal Ideation
Completed·Phase 2·ketamine

Study of NMDA Antagonists and Neuropathic Pain

University Hospital, Clermont-Ferrand

Neuropathic Pain
Completed·Phase 1·ketamine

A Study of LY2979165 and LY2140023 in Healthy Volunteers

Eli Lilly and Company

Healthy Volunteers
Completed·N/A·ketamine

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Completed·Phase 4·ketamine

Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults

Centre Hospitalier Universitaire de Nice

FractureDislocation
Completed·N/A·ketamine

Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation

Pr Isabelle CONSTANT

PainAnesthesia
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.